BIO CHEMISTRY MCQs by General knowledge Solutions

BIO CHEMISTRY MCQs      by General knowledge Solutions

                                                                             

01. Subacute combined degeneration of cord is caused due to deficiency of

• (A) Niacin
• (B) Cobalamin
• (C) Biotin
• (D) Thiamin

02. Vitamin required for metabolism of diols e.g. conversion of ethylene glycol to acetaldehyde is

•  (A) Thiamin
•  (B) Cobalamin
•  (C) Pyridoxine
•  (D) Folic acid

 03. Both folic acid and methyl cobalamin (vitamin B12) are required in

• (A) Deamination of serine
• (B) Deamination of threonine
• (C) Conversion of pyridoxal phosphate to pyridoxamine phosphate
• (D) Methylation of homocystein to methionine

 04. Folic acid or folate consists of the

• (A) Base pteridine, p-amino benzoic acid and asparate
• (B) Base purine, p-amino benzoic acid and glutamate
• (C) Base pteridine, p-amino benzoic acid and glutamate
• (D) Base purine, p-hydroxy benzoic acid and glutamate

05. Folate as a coenzyme is involved in the transfer and utilization of

• (A) Amino group
• (B) Hydroxyl group
• (C) Single carbon moiety
• (D) Amido group

06. Folic acid deficiency can be diagnosed by increased urinary excretion of

• (A) Methylmalonate
• (B) Figlu
• (C) Cystathionine
• (D) Creatinine

 07. Sulpha drugs interfere with bacterial synthesis of

• (A) Lipoate
• (B) Vitamin E
• (C) Tetrahydrofolate
•  (D) Ascorbic acid

08. Folate deficiency causes

• (A) Microcytic anemia
• (B) Hemolytic anemia
• (C) Iron deficiency anemia
• (D) Megaloblastic anemia

 09. Thiamin is heat stable in

•  (A) Acidic medium
• (B) Alkaline medium
• (C) Both (A) and (B)
• (D) None of these

 10. Thiamin deficiency includes

• (A) Mental depression
• (B) Fatigue
• (C) Beriberi
• (D) All of these

11. Thiamin diphosphate is required for oxidative decarboxylation of

• (A) α-Keto acids
•  (B) α-Amino acids
•  (C) Fatty acids
•  (D) All of these

 12. Loss of thiamin can be decreased by using

• (A) Unpolished rice
• (B) Parboiled rice
•  (C) Whole wheat flour
•  (D) All of the 

 13 . Daily requirement of thiamin is

• (A) 0.1 mg/1,000 Calories
•  (B) 0.5 mg/1,000 Calories
•  (C) 0.8 mg/1,000 Calories
• (D) 1.0 mg/1,000 Calories

14. Thiamin requirement is greater in

•  (A) Non-vegetarians
• (B) Alcoholics
• (C) Pregnant women
• (D) Both B and C

 15. People consuming polished rice as their staple food are prone to

•  (A) Beriberi
• (B) Pellagra
• (C) Both (A) and (B)
•  (D) None of these

 16. Riboflavin is heat stable in

• (A) Acidic medium
• (B) Alkaline medium
• (C) Neutral medium
• (D) Both (A) and (C)

17. FAD is a coenzyme for

• (A) Succinate dehydrogenase
•  (B) Glycerol-3-phosphate dehydrogenase
•  (C) Sphingosine reductase
• (D) All of these

18. Riboflavin deficiency can cause

•  (A) Peripheral neuritis
• (B) Diarrhoea
• (C) Angular stomatitis
• (D) None of thes 

 19. Pellagra preventing factor is

• (A) Thiamin
• (B) Riboflavin
• (C) Niacin
• (D) Pyridoxine

20. Niacin contains a

•  (A) Sulphydryl group
• (B) Carboxyl group
•  (C) Amide group
•  (D) All of these

21. NADP is required as a coenzyme in

•  (A) Glycolysis
• (B) Citric acid cycle
• (C) HMP shunt
•  (D) Gluconeogenesis

22. NAD is required as a coenzyme for

•  (A) Malate dehydrogenase
• (B) Succinate dehydrogenase
•  (C) Glucose-6-phosphate dehydrogenase
•  (D) HMG CoA reductae

 23. NAD is required as a conenzyme in

•  (A) Citric acid cycle
• (B) HMP shunt
• (C) β-Oxidation of fatty acids
• (D) Both (A) and (C)

24. Niacin can be synthesised in human beings from

• (A) Histidine
•  (B) Phenylalanine
• (C) Tyrosine
• (D) Tryptophan

25. Daily requirement of niacin is

•  (A) 5 mg
•  (B) 10 mg
• (C) 20 mg
• (D) 30 mg

 26. Niacin deficiency is common in people whose staple food is

•  (A) Wheat
• (B) Polished rice
• (C) Maize and /or sorghum
•  (D) None of these 

27. In pellagra, dermatitis usually affects

•  (A) Exposed parts of body
•  (B) Covered parts of body
• (C) Trunk only
• (D) All parts of the body

28. Niacin deficiency can occur in

•  (A) Hartnup disease
• (B) Phenylketonuria
• (C) Alkaptonuria
• (D) None of these

29. Pantothenic acid contains an amino acid which is

• (A) Aspartic acid
• (B) Glutamic acid
• (C) β-Alanine
• (D) β-Aminoisobutyric acid

30. Sulphydryl group of coenzyme a is contributed by

•  (A) β-Alanine
• (B) β-Aminoisobutyric acid
• (C) Methionine
•  (D) Thioethanolamine

 31. Coenzyme A contains a nitrogenous base which is

• (A) Adenine
• (B) Guanine
• (C) Choline
• (D) Ethanolamine

 32. The following is required for the formation of coenyzme A:

• (A) ATP
• (B) GTP
• (C) CTP
• (D) None of these 

 33. Coenzyme A is required for catabolism of

•  (A) Leucine
• (B) Isoleucine
• (C) Valine
• (D) All of these

34. Deficiency of pantothenic acid in human beings can affect

• (A) Nervous system
• (B) Digestive system
• (C) Both (A) and (B)
• (D) None of these

 35. Pyridoxal phosphate is a coenzyme for

• (A) Glutamate oxaloacetate transaminase
• (B) Glutamate pyruvate transaminase
•  (C) Tyrosine transaminase
• (D) All of these

36. Pyridoxal phosphate is required as a coenzyme in

• (A) Transamination
• (B) Transulphuration
• (C) Desulphydration
• (D) All of these

 37. Pyridoxal phosphate is a coenzyme for

• (A) Glycogen synthetase
• (B) Phosphorylase
• (C) Both (A) and (B)
• (D) None of these

38. Pyridoxine deficiency can be diagnosed by measuring urinary excretion of

•  (A) Pyruvic acid
• (B) Oxaloacetic acid
• (C) Xanthurenic acid
•  (D) None of these

39. Pyridoxine deficiency can be diagnosed by measuring the urinary excretion of xanthurenic acid following a test dose of

• (A) Glycine
• (B) Histidine
• (C) Tryptophan
• (D) Pyridoxine

40. Pyridoxine requirement depends upon the intake of

• (A) Carbohydrates
• (B) Proteins
• (C) Fats
• (D) None of these

 41. Anti-egg white injury factor is

• (A) Pyridoxine
• (B) Biton
• (C) Thiamin
• (D) Liponic acid

42. When eggs are cooked

• (A) Biotin is destroyed but avidin remains unaffected
• (B) Avidin is inactivated but biotin remains unaffected
• (C) Both avidin and biotin are inactivated
• (D) Both avidin and biotin remain unaffected

 43. Biotin is required as a coenzyme by

• (A) Anaerobic dehydrogenases
• (B) Decarboxylases
• (C) Aerobic dehydrogenases
• (D) Carboxylases

44. Biotin is a coenzyme for

• (A) Pyruvate carboxylase
• (B) Acetyl CoA carboxylase
• (C) Propionyl CoA carboxylase
• (D) All of these

45. Lipoic acid is a conenzyme for

• (A) Pyruvate dehydrogenase
• (B) α-Ketoglutarate dehydrogenae
• (C) Both (A) and (B)
• (D) None of these

46. Chemically, lipoic acid is

• (A) Saturated fatty acid
• (B) Unsaturated fatty acid
• (C) Amino acid
• (D) Sulphur containing fatty acid

01. B 02. B 03. D 04. C 05. C 06. B 07. C 08. D 09. A 10. D 11. A 12. D 13. B 14. D 15. A 16. D 17. D 18. C 19. C 20. B 21. C 22. A 23. D 24. D 25. C 26. C 27. A 28. A 29. C 30. D 31. A 32. A 33. D 134. C 135. D 136. D37. B 38. C 39. C 40. B 41. B 42. B 43. D 44. D 45. C 46. D