BIO CHEMISTRY MCQs (PART 1) by General knowledge Solutions

   BIO CHEMISTRY MCQs (PART 1)   by General knowledge Solutions

                                                                           

1. Folic acid contains

• (A) Pteridine
• (B) p-Amino benzoic acid
• (C) Glutamic acid
• (D) All of these

2. Conversion of folate into tetrahydrofolate requires

• (A) NADH
• (B) NADPH
• (C) FMNH2
• (D) FADH2

3. Riboflavin deficiency symptoms are

•  (A) Glossitis
• (B) stomatis
• (C) Vomitting
•  (D) Both (A) and (B)

4. Vitamin B12 forms coenzymes known as

• (A) Cobamide
• (B) Transcobalamin I
• (C) Transcobalamin II
•  (D) Both (B) and (C)

 5. Methylcobalamin is required for formation of

•  (A) Serin from glycine
• (B) Glycine from serine
• (C) Methionine from homocysteine
•  (D) All of these

6. Absorption of Vitamin B12 requires the presence of

•  (A) Pepsin
• (B) Hydrochloric acid
•  (C) Intrinsic factor
•  (D) Boh (B) and (C)

7. Intrinsic factor is chemically a

•  (A) Protein
• (B) Glycoprotein
• (C) Mucopolysaccaride
•  (D) Peptide

8. Chemically, Extrinsic Factor of Castle is a

• (A) Mucoprotein
• (B) Glycoprotein
• (C) Mucopolysaccharide
• (D) Cyanocobalaminm

 9. Vitamin B12 is

• (A) Not stored in the body
• (B) Stored in bone marrow
• (C) Stored in liver
• (D) Stored in RE cells

10. Vitamin B12 is transported in blood by

• (A) Albumin
• (B) Transcortin
• (C) Transcobalamin I
• (D) Transcobalamin II

11. Vitamin B12 is synthesized by

•  (A) Bacteria only
• (B) Plants only
• (C) Animals only
• (D) Both (A) and (C)

 12. Deficiency of vitamin B12 can occur because of

• (A) Decreased intake of vitamin B12
• (B) Atrophy of gastric mucosa
• (C) Intestinal malabsorption
• (D) All of these

 13. Deficiency of vitamin B12 can be diagonised by

•  (A) Carr-Price reaction
• (B) Ames assay
• (C) Watson-Schwartz test
• (D) Schilling test

 14. Gastyrectomy leads to megaloblastic anaemia within a few

• (A) Days
•  (B) Weeks
•  (C) Months
• (D) Years

 15. Ascorbic acid is required to synthesise all of the following except

•  (A) Collagen
•  (B) Bile acids
•  (C) Bile pigments
• (D) Epinephrine

 16. Vitamin C enhances the intestinal absorption of

• (A) Potassium
• (B) Iodine
• (C) Iron
• (D) None of these

 17. Vitamin C activity is present in

• (A) D-Ascorbic acid
• (B) D-Dehydroascorbic acid
• (C) L-Ascorbic acid
• (D) Both A and B

18. Vitamin C is required for the synthesis of

• (A) Bile acids from cholesterol
• (B) Bile salts from bile acids
• (C) Vitamin D from cholesterol
• (D) All of these

 19. Deficiency of vitamin C causes

• (A) Beriberi
• (B) Pellagra
• (C) Pernicious anaemia
•  (D) Scurvy

20. An early diagnosis of vitamin C deficiency can be made by

• (A) Measuring plasma ascorbic acid
•  (B) Measuring urinary ascorbic acid
• (C) Ascorbic acid saturation test
• (D) All of these

 21. Daily requirement of vitamin C in adults is about

•  (A) 100 mg
• (B) 25 mg
• (C) 70 mg
•  (D) 100 mg

 22. The vitamin having the highest daily requirement among the following is

• (A) Thiamin
• (B) Ribovflavin
• (C) Pyridoxine
• (D) Ascorbic acid

23. Anaemia can occur due to the deficiency of all the following except

• (A) Thiamin
• (B) Pyridoxine
• (C) Folic acid
• (D) Cyanocobalamin

24. A vitamin which can be synthesized by human beings is

• (A) Thiamin
•  (B) Niacin
• (C) Folic acid
• (D) Cyanocobalamin

25. Laboratory diagnosis of vitamin B12 deficiency can be made by measuring the urinary excretion of 

• (A) Xanthurenic acid
• (B) Formiminoglutamic acid
• (C) Methylmalonic acid
• (D) Homogentisic acid

 26. The molecule of vitamin A1 contains

• (A) Benzene ring
• (B) β-Ionone ring
• (C) β-Carotene ring
• (D) None of these

27. Precursor of Vitamin A is

• (A) α-Carotene
• (B) β-Carotene
• (C) γ-Carotene
• (D) All of these

28. Two molecules of vitamin A can be formed from 1 molecule of

• (A) α-Carotene
• (B) β-Carotene
• (C) γ-Carotene
• (D) All of these

 29. Conversion of β-carotene into retinal requires the presence of

• (A) β-Carotene dioxygenase
• (B) Bile salts
•  (C) Molecular oxygen
• (D) All of these

 30. Conversion of retinal into ritonal requires the presence of

•  (A) NADH
• (B) NADPH
• (C) FADH2
• (D) Lipoic acid

31. Retinal is converted into retinoic acid in the presence of

• (A) Retinal oxidase
• (B) Retinal carboxylase
• (C) Retinene reductase
• (D) Spontaneously

 32. Vitamin A absorbed in intestine is released into

• (A) Portal circulation
• (B) Lacteals
• (C) Both (A) and (B)
• (D) None of these

33. Vitamin A is stored in the body in

• (A) Liver
• (B) Adipose tissue
•  (C) Reticuloendothelial cells
•  (D) All of these

34. Rhodopsin contains opsin and

• (A) 11-cis-retinal
• (B) 11-trans-retinal
• (C) All-cis-retinal
• (D) All trans-retinal

 35. When light falls on rod cells

• (A) All-cis-retinal is converted into all-trans-retinal
• (B) 11-cis-retinal is converted into 11-trans-retinal
•  (C) 11-trans-retinal is converted into all-transretinal
•  (D) 11-cis-retinal is converted into all-trans-retinal

 36. Conversion of all-trans-retinal into alltrans-retinol requires

•  (A) NAD
• (B) NADH
• (C) NADP
•  (D) NADPH

 37. Retinol isomerase is present in

•  (A) Retina
•  (B) Liver
• (C) Both (A) and (B)
• (D) None of these

 38. Anti-oxidant activity is present in

• (A) β-Carotene
• (B) Retinol
• (C) Retinoic acid
• (D) All of these

39. One international Unit of vitamin A is the activity present in

• (A) 0.3 µg of β-Carotene
• (B) 0.3 µg of retino
• (C) 0.6 µg of retinoic acid
•  (D) All of these

 40. Daily requirement of vitamin A in an adult man can be expressed as

• (A) 400 IU
• (B) 1,000 IU
• (C) 5,000 IU
• (D) 10,000 IU

41. Vitamin B6 includes

• (A) Pyridoxal
• (B) Pyridoxamine
• (C) Pyridoxine
• (D) All of these

42. An early effect of vitamin a deficiency is

• (A) Xerophthalmia
• (B) Keratomalacia
• (C) Prolonged dark adaptation time
• (D) Follicular hyperkeratosis

 43. Nyctalopia is

• (A) Drying of eyes
• (B) Destruction of cornea
•  (C) Blindness
•  (D) Inability to see in dimlight

 44. Rod cells possess a trans-membrane protein which is

• (A) Adenylate cyclase
• (B) Transducin
• (C) Rhodopsin
• (D) B as well as C

 45. Provitamins A include

• (A) Retinal
• (B) Retionic acid
• (C) Carotenes
• (D) All of these

 46. Retinoic acid can

• (A) Act as a photo receptor
• (B) Support growth and differentiation
• (C) Act as an anti-oxidant
• (D) None of these

ANSWER

1. D 2. B 3. D 4. A 5. C 6. D 7. B 8. D 9. C 10. D 11. A 12. D 13. D 14. D 15. C 16. C 17. C 18. A 19. D 20. C 21. C 22. D 23. A 24. B 25. C 26. B 27. D 28. B 29. D 30. B 31. D 32. B 33. A 34. A 35. D 36. D 37. B 38. A 39. B 40. C 41. D 42. C 43. D 44. C 45. C 46. B