BIO CHEMISTRY MCQs (PART 3) by General knowledge Solutions

BIO CHEMISTRY MCQs (PART 3)  by General knowledge Solutions

                                                                         

1. In the individuals who are given liberal quantities of vitamin C, the serum ascorbic acid level is

•  (A) 1–1.4 µg/100 ml
• (B) 2–4 µg/100 ml
• (C) 1–10 µg/100 ml
• (D) 10–20 µg/100 ml

 2. The vitamin which would most likely become deficient in an individual who develop a completely carnivorous life style is

• (A) Thiamin
• (B) Niacin
• (C) Vitamin C
• (D) Cobalamin

 3. In human body highest concentration of ascorbic acid is found in

•  (A) Liver
• (B) Adrenal cortex
•  (C) Adrenal medulla
•  (D) Spleen

 4. The vitamin required for the formation of hydroxyproline (in collagen) is

• (A) Vitamin C
• (B) Vitamin A
• (C) Vitamin D
• (D) Vitamin E

5. Vitamin required for the conversion of phydroxyphenylpyruvate to homogentisate is

• (A) Folacin
• (B) Cobalamin
• (C) Ascorbic acid
• (D) Niacin

6. Vitamin required in conversion of folic acid to folinic acid is

• (A) Biotin
• (B) Cobalamin
• (C) Ascorbic acid
• (D) Niacin

7. Ascorbic acid can reduce

• (A) 2, 6-Dibromobenzene
• (B) 2, 6-Diiodoxypyridine
• (C) 2, 6-Dichlorophenol indophenol
• (D) 2, 4-Dinitrobenzene

8. Sterilised milk lacks in

• (A) Vitamin A
• (B) Vitamin D
• (C) Vitamin C
• (D) Thiamin

 9. Scurvy is caused due to the deficiency of

• (A) Vitamin A
• (B) Vitamin D
• (C) Vitamin K
• (D) Vitamin C

 10. Both Wernicke’s disease and beriberi can be reversed by administrating

• (A) Retinol
• (B) Thiamin
• (C) Pyridoxine
• (D) Vitamin B12

 11. The Vitamin B1 deficiency causes

• (A) Ricket
• (B) Nyctalopia
• (C) Beriberi
• (D) Pellagra

12. Concentration of pyruvic acid and lactic acid in blood is increased due to deficiency of the vitamin

• (A) Thiamin
• (B) Riboflavin
• (C) Niacin
• (D) Pantothenic acid

 13. Vitamin B1 coenzyme (TPP) is involved in

• (A) Oxidative decarboxylation
• (B) Hydroxylation
• (C) Transamination
•  (D) Carboxylation

14. Increased glucose consumption increases the dietary requirement for

• (A) Pyridoxine
• (B) Niacin
• (C) Biotin
• (D) Thiamin

 15. Thiamin is oxidized to thiochrome in alkaline solution by

• (A) Potassium permanganate
• (B) Potassium ferricyanide
• (C) Potassium chlorate
• (D) Potassium dichromate

16. Riboflavin is a coenzyme in the reaction catalysed by the enzyme

• (A) Acyl CoA synthetase
• (B) Acyl CoA dehydrogenase
• (C) β-Hydroxy acyl CoA
• (D) Enoyl CoA dehydrogenase

17. The daily requirement of riboflavin for adult in mg is

• (A) 0–1.0
• (B) 1.2–1.7
• (C) 2.0–3.5
• (D) 4.0–8.0

18. In new born infants phototherapy may cause hyperbilirubinemia with deficiency of

• (A) Thiamin
• (B) Riboflavin
• (C) Ascorbic acid
• (D) Pantothenic acid

19. Riboflavin deficiency causes

• (A) Cheilosis
• (B) Loss of weight
• (C) Mental deterioration
•  (D) Dermatitis

20. Magenta tongue is found in the deficiency of the vitamin

• (A) Riboflavin
• (B) Thiamin
• (C) Nicotinic acid
• (D) Pyridoxine

 21. Corneal vascularisation is found in deficiency of the vitamin:

•  (A) B1
• (B) B2
• (C) B3
• (D) B6

 22. The pellagra preventive factor is

• (A) Riboflavin
• (B) Pantothenic acid
• (C) Niacin
• (D) Pyridoxine

 23. Pellagra is caused due to the deficiency of

• (A) Ascorbic acid
• (B) Pantothenic acid
• (C) Pyridoxine
• (D) Niacin

 24. Niacin or nicotinic acid is a monocarboxylic acid derivative of

• (A) Pyridine
•  (B) Pyrimidine
• (C) Flavin
• (D) Adenine

 25. Niacin is synthesized in the body from

• (A) Tryptophan
• (B) Tyrosine
• (C) Glutamate
• (D) Aspartate

26. The proteins present in maize are deficient in

• (A) Lysine
• (B) Threonine
• (C) Tryptophan
• (D) Tyrosine

 27. Niacin is present in maize in the form of

• (A) Niatin
• (B) Nicotin
• (C) Niacytin
• (D) Nicyn

 28. In the body 1 mg of niacin can be produced from

•  (A) 60 mg of pyridoxine
•  (B) 60 mg of tryptophan
•  (C) 30 mg of tryptophan
• (D) 30 mg of pantothenic acid

 29. Pellagra occurs in population dependent on

• (A) Wheat
• (B) Rice
• (C) Maize
• (D) Milk

 30. The enzymes with which nicotinamide act as coenzyme are

• (A) Dehydrogenases
• (B) Transaminases
• (C) Decarboxylases
• (D) Carboxylases

31. Dietary requirement of Vitamin D:

• (A) 400 I.U.
• (B) 1000 I.U.
• (C) 6000 I.U.
• (D) 700 I.U.

 32. The Vitamin which does not contain a ring in the structure is

• (A) Pantothenic acid
• (B) Vitamin D
• (C) Riboflavin
•  (D) Thiamin

 33. Pantothenic acid is a constituent of the coenzyme involved in

• (A) Decarboxylation
• (B) Dehydrogenation
•  (C) Acetylation
• (D) Oxidation

34. The precursor of CoA is

• (A) Riboflavin
• (B) Pyridoxamine
• (C) Thiamin
• (D) Pantothenate

 35. ‘Burn ing foot syndrome’ has been ascribed to the deficiency of

• (A) Pantothenic acid
• (B) Thiamin
• (C) Cobalamin
• (D) Pyridoxine

36. Pyridoxal phosphate is central to

• (A) Deamination
• (B) Amidation
• (C) Carboxylation
• (D) Transamination

 37. The vitamin required as coenzyme for the action of transaminases is

• (A) Niacin
• (B) Pantothenic acid
• (C) Pyridoxal phosphate
•  (D) Riboflavin

38. Vitamin B6 deficiency may occur during therapy with

• (A) Isoniazid
• (B) Terramycin
• (C) Sulpha drugs
• (D) Aspirin

39. Deficiency of vitamin B6 may occur in

• (A) Obese person
• (B) Thin person
• (C) Alcoholics
• (D) Diabetics

 40. ‘Xanthurenic acid index’ is a reliable criterion for the deficiency of the vitamin

• (A) Pyridoxal
• (B) Thiamin
• (C) Pantothenic acid
• (D) Cobalamin

 41. Epileptiform convulsion in human infants have been attributed to the deficiency of the vitamin

• (A) B1
• (B) B2
• (C) B6
• (D) B12

 42. Biotin is a coenzyme of the enzyme

•  (A) Carboxylase
• (B) Hydroxylase
•  (C) Decarboxylase
•  (D) Deaminase

 43. The coenzyme required for conversion of pyruvate to oxaloacetate is

• (A) FAD
• (B) NAD
• (C) TPP
• (D) Biotin

 44. In biotin-containing enzymes, the biotin is bound to the enzyme by

• (A) An amide linkage to carboxyl group of glutamine
• (B) A covalent bond with CO2
• (C) An amide linkage to an amino group of lysine
• (D) An amide linkage to α-carboxyl group of protein

 45. A molecule of CO2 is captured by biotin when it acts as coenzyme for carboxylation reaction. The carboxyl group is covalently attached to

• (A) A nitrogen (N1) of the biotin molecule
• (B) Sulphur of thiophene ring
• (C) α-Amino group of lysine
• (D) α-Amino group of protein

 46. Consumption of raw eggs can cause deficiency of

• (A) Biotin
• (B) Pantothenic acid
• (C) Riboflavin
• (D) Thiamin

47. The cofactor or its derivative required for the conversion of acetyl CoA to malonylCoA is

• (A) FAD
• (B) ACP
• (C) NAD+
• (D) Biotin

 48. A cofactor required in oxidative decarboxylation of pyruvate is

•  (A) Lipoate
• (B) Pantothenic acid
• (C) Biotin
• (D) Para aminobenzoic acid

 49. The central structure of B12 referred to as corrin ring system consists of

• (A) Cobalt
• (B) Manganese
• (C) Magnesium
• (D) Iron

 50. The central heavy metal cobalt of vitamin B12 is coordinately bound to

• (A) Cyanide group
• (B) Amino group
• (C) Carboxyl group
• (D) Sulphide group

51. Vitamin B12 has a complex ring structure (corrin ring) consisting of four

• (A) Purine rings
• (B) Pyrimidine rings
• (C) Pyrrole rings
• (D) Pteridine rings

52. Emperical formula of cobalamin is

• (A) C63H88N12O14P.CO
• (B) C61H82N12O12P.CO
• (C) C61H88N12O14P.CO
• (D) C63H88N14O14P.CO

53. A deficiency of vitamin B12 causes

•  (A) Beri-Beri
• (B) Scurvy
• (C) Perniciuos anemia
• (D) Ricket

54. Vitamin B12 deficiency can be diagnosed by urinary excretion of

• (A) Pyruvate
• (B) Methylmalonate
• (C) Malate

1. A 2. C 3. B 4. A 5. D 6. C 7. C 8. C 9. D 10. B 11. C 12. A 13. A 14. D 15. B 16. B 17. B 18. B 19. A 20.A 21. B 22. C 23. D 24. A 25. A 26. C 27. C 28. B 29. C 30. A 31. A 32. A 33. C 34. D 35. A 36. D 37. C 38. A 39. C 40. A 41. C 42. A 43. D 44. C 45. A 46. A 47. D 48. A 49. A 50. A 51. C 52. D 53. C 54. B