BIO CHEMISTRY MCQs (PART 2)

BIO CHEMISTRY MCQs (PART 2)

1. The filtration factor tends to be normal in
(A) Early essential hypertension
(B) Malignant phase of hypertension
(C) Glomerulonephritis
(D) Acute nephritis

 2. The filtration factor is increased in
 (A) Glomerulonephritis
(B) Malignant phase of hypertension
(C) Early essential hypertension
(D) Acute nephritis

3. The filtration factor is decreased in
(A) Glomerulonephritis
(B) Early essential hypertension
(C) Malignant phase of hypertension
(D) Starvation

4. Excretion of phenolsulphanpthalein (PSP) reflects
(A) Glomerulonephritis
(B) Maximaltabular excretory capacity
(C) Filtration factor
(D) Renal plasma flow


5. Which of the following is a polyunsaturated fatty acid?
(A) Palmitic acid
(B) Palmitoleic acid
(C) Linoleic acid
(D) Oleic acid

6 Which of the following is omega-3 polyunsaturated fatty acid?
 (A) Linoleic acid
(B) α-Linolenic acid
 (C) γ-Linolenic acid
 (D) Arachidonic acid


7 Triglycerides are
(A) Heavier than water
 (B) Major constituents of membranes
(C) Non-polar
(D) Hydrophilic

8 Cerebronic acid is present in
 (A) Glycerophospholipids
 (B) Sphingophospholipids
 (C) Galactosyl ceramide
 (D) Gangliosides

9 Acylsphingosine is also known as
(A) Sphingomyelin
(B) Ceramide
(C) Cerebroside
(D) Sulphatide

10.The highest phospholipids content is found in
(A) Chylomicrons
(B) VLDL
(C) LDL
(D) HDL


11The major lipid in chylomicrons is
(A) Triglycerides
(B) Phospholipids
(C) Cholesterol
(D) Free fatty acids

12 Number of carbon atoms in cholesterol is
(A) 17
(B) 19
(C) 27
(D) 30

 13 The lipoprotein richest in cholesterol is
(A) Chylomicrons
(B) VLDL
(C) LDL
(D) HDL

14The major storage form of lipids is
(A) Esterified cholesterol
(B) Glycerophospholipids
(C) Triglycerides
(D) Sphingolipids

15 Cerebonic acid is present in
(A) Triglycerides
(B) Cerebrosides
(C) Esterified cholestrol
(D) Sphingomyelin

 16 The nitrogenous base in lecithin is
(A) Ethanolamine
(B) Choline
(C) Serine
(D) Betaine

17 All the following are omega-6-fatty acids except
(A) Linoleic acid
(B) α-Linolenic acid
(C) γ-Linolenic acid
(D) Arachidonic acid

 18 All the following have 18 carbon atoms except
(A) Linoleic acid
(B) Linolenic acid
(C) Arachidonic acid
(D) Stearic acid

19 A 20-carbon fatty acid among the following is
(A) Linoleic acid
(B) α -Linolenic acid
(C) β -Linolenic acid
(D) Arachidonic acid


20 Triglycerides are transported from liver to extrahepatic tissues by
 (A) Chylomicrons
 (B) VLDL
 (C) HDL
 (D) LDL

 21 Cholesterol is transported from liver to extrahepatic tissues by
 (A) Chylomicrons
 (B) VLDL
 (C) HDL
 (D) LDL


 22 Elevated plasma level of the following projects against atherosclerosis:
(A) Chylomicrons
(B) VLDL
(C) HDL
(D) LDL

 23All the following amino acids are nonessential except
(A) Alanine
(B) Histidine
(C) Cysteine
(D) Proline

 24 Sulphydryl group is present in
(A) Cysteine
(B) Methionine
(C) Both (A) and (B)
(D) None of these

 25 Oligosaccharide-pyrophosphoryl dolichol is required for the synthesis of
(A) N-linked glycoproteins
(B) O-linked glycoproteins
(C) GPI-linked glycoproteins
(D) All of these


26 In N-linked glycoproteins, oligosaccharide is attached to protein through its
(A) Asparagine residue
(B) Glutamine residue
(C) Arginine residue
(D) Lysine residue

 27 De hovo synthesis of fatty acids occurs in
(A) Cytosol
(B) Mitochondria
(C) Microsomes
(D) All of these

 28 Acyl Carrier Protein contains the vitamin:
(A) Biotin
(B) Lipoic acid
(C) Pantothenic acid
(D) Folic acid

 29 Which of the following is required as a reductant in fatty acid synthesis?
(A) NADH
(B) NADPH
(C) FADH2
(D) FMNH2

30 Hepatic liponenesis is stimulated by:
(A) cAMP
(B) Glucagon
(C) Epinephrine
(D) Insulin

 31 De novo synthesis of fatty acids requires all of the following except
(A) Biotin
(B) NADH
(C) Panthothenic acid
(D) ATP

 32 Acetyl CoA carboxylase regulates fatty acid synthesis by which of the following mechanism? (A) Allosteric regulation
(B) Covalent modification
(C) Induction and repression
(D) All of these

33 β-Oxidation of fatty acids requires all the following coenzymes except
(A) CoA
(B) FAD
(C) NAD
(D) NADP


34 Which of the following can be oxidized by β-oxidation pathway?
(A) Saturated fatty acids
(B) Monosaturated fatty acids
(C) Polyunsaturated fatty acids
(D) All of these


 35 Propionyl CoA is formed on oxidation of
(A) Monounsaturated fatty acids
(B) Polyunsaturated fatty acids
(C) Fatty acids with odd number of carbon atoms
(D) None of these

36 An enzyme required for the synthesis of ketone bodies as well as cholesterol is
(A) Acetyl CoA carboxylase
(B) HMG CoA synthetase
(C) HMG CoA reductase
(D) HMG CoA lyase


37Ketone bodies are synthesized in
(A) Adipose tissue
(B) Liver
(C) Muscles
(D) Brain



38 All the following statements about ketone bodies are true except
(A) Their synthesis increases in diabetes mellitus
(B) They are synthesized in mitchondria
(C) They can deplete the alkali reserve
(D) They can be oxidized in the liver


 39 All the following statements about carnitine are true except
(A) It can be synthesised in the human body
(B) It can be synthesized from methionine and lysine
(C) It is required for transport of short chain fatty acids into mitochondria
(D) Its deficiency can occur due to haemodialysis


40 Which of the following can be synthesized in the human body if precurors are available?
 (A) Oleic acid
 (B) Palmitoleic acid
 (C) Arachidonic acid
 (D) All of these


42 All the following can be oxidized by β- oxidation except
(A) Palmitic acid
(B) Phytanic acid
(C) Linoleic acid
(D) Fatty acids having an odd number of carbon atoms


42 Anti-inflammatory corticosteroids inhibit the synthesis of
(A) Leukotrienes
(B) Prostaglandins
(C) Thromboxanes
(D) All of these


 43 Diets having a high ratio of polyunsaturated: saturated fatty acids can cause
(A) Increase in serum triglycerides
(B) Decrease in serum cholesterol
(C) Decrease in serum HDL
(D) Skin lesions


 44 Thromboxanes cause
(A) Vasodilation
(B) Bronchoconstriction
(C) Platelet aggregation
(D) All of these

 45 Prostaglandins lower camp in
(A) Adipose tissue
(B) Lungs
(C) Platelets
(D) Adenohypophysis

 46 Slow reacting Substance of Anaphylaxis is a mixture of
(A) Prostaglandins
(B) Prostacyclins
(C) Thromboxanes
(D) Leukotrienes

 47 Dipalmitoyl lecithin acts as
(A) Platelet activating factor
(B) Second messenger for hormones
(C) Lung surfactant
(D) Anti-ketogenic compound

 48 Reichert-Meissl number:
(A) 0.1 N KOH
(B) 0.5 KOH
(C) 0.1 N NaOH
(D) 0.5 NaOH


49 In glycerophospholipids, a polyunsaturated fatty acid is commonly attached to which of the following carbon atom of glycerol?
(A) Carbon 1
(B) Carbon 2
(C) Both (A) and (B)
(D) None of these

 50 Lysolecithin is formed from lecithin by removal of
(A) Fatty acid from position 1
(B) Fatty acid from position 2
(C) Phosphorylcholine
(D) Choline

 51 Sphingosine is synthesized from
(A) Palmitoyl CoA and Choline
(B) Palmitoyl CoA and ethanolamine
(C) Palmitoyl CoA and serine
(D) Acetyl CoA and choline

52 For synthesis of sphingosine, all the following coenzymes are required except
(A) Pyridoxal phosphate
(B) NADPH
(C) FAD
(D) NAD