BIO CHEMISTRY MCQs (PART 1)
BIO CHEMISTRY MCQs (PART 1)
00. The ability of
liver to remove a dye like BSP from the blood suggests a normal
(A) Excretory function
(B) Detoxification function
(C) Metabolic function
(D) Circulatory function
01. Removal of BSP
dye by the liver involves conjugation with
(A) Thiosulphate
(B) Glutamine
(C) Cystein component of glutathione
(D) UDP glucuronate
02. Normal value of
plasma total proteins varies between
(A) 3–4 gm/100ml
(B) 6–8 gm/100ml
(C) 10–12 gm/100ml
(D) 14–16 gm/100ml
03. A decrease in albumin with increased production of
other unidentified proteins which migrate in β, γ region suggests
(A) Cirrhosis of liver
(B) Nephrotic syndrome
(C) Infection
(D) Chronic lymphatic leukemia
04. In increase in
α2-Globulin with loss of albumin in urine suggests
(A) Primary immune
deficiency
(B) Nephrotic syndrome
(C) Cirrhosis of liver
(D) Multiple myeloma
05. The normal levels of prothrombin time is about
(A) 2 sec
(B) 4 sec
(C) 14 sec
(D) 10–16 sec
06. In obstructive
jaundice prothrombin time
(A) Remains normal
(B) Decreases
(C) Responds to vit K and becomes normal
(D) Responds to vit K
and increases
07. In parenhymatous
liver disease the prothrombin time
(A) Remains normal
(B) Increases
(C) Decreases
(D) Responds to Vit K
08. Urea clearance test is used to determine the
(A) Glomerular filtration rate
(B) Renal plasma flow
(C) Ability of kidney to concentrate the urine
(D) Measurement of tubular mass
09. The formula to
calculate maximum urea clearance is U V× B , where U denotes
(A) Concentration of urea in urine in gm/24hr
(B) Concentration of urea in urine in mg/100 ml
(C) Concentration of urea in blood in mg/100 ml
(D) Volume of urine
in ml/mt
10. Average maximum
urea clearance is
(A) 30 ml
(B) 50 ml
(C) 75 ml
(D) 90 ml
11. The average normal value for standard urea clearance is
(A) 20 ml
(B) 30 ml
(C) 40 ml
(D) 54 ml
12. Urea clearance is lowered in
(A) Acute nephritis
(B) Pneumonia
(C) Early stage of
nephritic syndrome
(D) Benign hypertension
13. Glomerular filtration rate can be measured by
(A) Endogenous creatinine clearance
(B) Para-aminohippurate test
(C) Addis test
(D) Mosenthal test
14. At normal levels
of creatinine in the blood, this metabolite is
(A) Filtered at the glomerulus but not secreted nor
reabsorbed by the tubule
(B) Secreted by the tubule
(C) Reabsorbed by the tubule
(D) Secreted and reabsorbed by tubul
15. The normal
values for creatinine clearance varies from
(A) 20–40 ml/min
(B) 40–60 ml/min
(C) 70–85 ml/min
(D) 95–105 ml/min
16. Measurement of
insulin clearance test is a measure of
(A) Glomerular filtration rate
(B) Filtration factor
(C) Renal plasma flow
(D) Tubular secretory mass
17. The polysaccharide insulin is
(A) Filtered at the glomerulus but neither secreted nor
reabsorbed by the tubule
(B) Filtered at the glomerulus and secreted by the tubule
(C) Filtered at the glomerulus and reabsorbed by the tubule
(D) Filtered at the glomerulus, secreted and reabsorbed by
the tubule
18. Normal insulin clearance is
(A) 40 ml/1.73 sqm
(B) 60 ml/1.73 sqm
(C) 80 ml/1.73 sqm
(D) 120 ml/1.73 sqm
19. Creatinine EDTA
clearance is a test to measure
(A) Renal plasma flow
(B) Filtration fraction
(C) Glomerular filtration rate
(D) Tubular function
20. The end products
of saponification:
(A) glycerol
(B) acid
(C) soap
(D) Both (A) and (C)
21. The normal PAH clearance for a surface area of 1.73
sqm. Is
(A) 200 ml/min
(B) 300 ml/min
(C) 400 ml/min
(D) 574 ml/min
22. Para amino
hippurate is
(A) Filtered at glomeruli and secreted by the tubules
(B) Filtered at glomeruli and not secreted by the tubules
(C) Filtered at glomeruli and reabsorbed completely
(D) Not removed completely during a single circulation of
the blood through the kidney.
23. The Tm for PAH i.e the maximal secretory capacity of
the tubule for PAH can be used to gavge the
(A) Extent of tubular damage
(B) Impairment of the capacity of the tubule to perform
osmotic work
(C) Impairment of renal plasma flow
(D) Glomerular filtration rate
24. The normal Tm in mg/min/1.73 sqm for PAH is
(A) 20
(B) 40
(C) 60
(D) 80
25. The normal range
of filtration factor in an adult is
(A) 0.10–0.15
(B) 0.16–0.21
(C) 0.25–0.30
(D) 0.35–0.40
26. Hepatocellular jaundice as compared to pure obstructive
type of jaundice is characterized by
(A) Increased serum alkaline phosphate, LDH and ALT
(B) Decreased serum alkaline phosphatase, LDH and ALT
(C) Increased serum alkaline phosphatase and decreased levels
of LDH and ALT
(D) Decreased serum alkaline phosphatase and increased serum
LDH and ALT
27. Icteric index of
an normal adult varies between
(A) 1–2
(B) 2–4
(C) 4–6
(D) 10–15
28. Clinical jaundice is present with an icteric index above
(A) 4
(B) 8
(C) 10
(D) 15
29. Normal quantity
of urobilinogen excreted in the feces per day is about
(A) 10–25 mg
(B) 50–250 mg
(C) 300–500 mg
(D) 700–800 mg
30. Fecal urobilinogen is decreased in
(A) Obstruction of
biliary duct
(B) Hemolytic jaundice
(C) Excess fat intake
(D) Low fat intake
31. A complete
absence of fecal urobilinogen is strongly suggestive of
(A) Obstruction of
bile duct
(B) Hemolytic jaundice
(C) Intrahepatic cholestasis
(D) Malignant obstructive disease
32. Immediate direct Vanden Bergh reaction indicates
(A) Hemolytic jaundice
(B) Hepatic jaundice
(C) Obstructive jaundice
(D) Megalobastic anemia
33. The presence of
bilirubin in the urine without urobilinogen suggests
(A) Obstructive jaundice
(B) Hemolytic jaundice
(C) Pernicious anemia
(D) Damage to the hepatic parenchyma
34. Impaired
galactose tolerance test suggests
(A) Defect in glucose utilisation
(B) Liver cell injury
(C) Renal defect
(D) Muscle injury
35. Increased serum
ornithine carabamoyl transferase activity is diagnostic of
(A) Myocardial infarction
(B) Hemolytic jaundice
(C) Bone disease
(D) Acute viral hepatitis
36. The best known
and most frequently used test of the detoxicating functions of liver is
(A) Hippuric acid test
(B) Galactose tolerance test
(C) Epinephrine tolerance test
(D) Rose Bengal dye test
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