BIO CHEMISTRY MCQs (PART 3) by General knowledge Solutions
BIO CHEMISTRY MCQs (PART3) by General knowledge Solutions
1. Cerebrosides contain all the following except
2. Niemann-Pick disease results from deficiency of
3. Chylomicron remnants are catabolised in
4. VLDL remnant may be converted into
5. Receptors for chylomicron remnants are
6. LDL receptor is specific for
7. Nascent HDL of intestinal origin lacks
8. HDL is synthesized in
9. Nascent HDL of intestinal origin acquires Apo C and Apo E from
10. Heparin releasable hepatic lipase converts
11. Activated lecithin cholesterol acyl transferase is essential for the conversion of
12. Fatty liver may be caused by
13. Alcohol dehydrogenase converts ethanol into
14. Lipids are stored in the body mainly in the form of
15. Lipid stores are mainly present in
16. Glycerol is converted into glycerol-3- phosphate by
17. In adipose tissue, glycerol-3-phosphate required for the synthesis of triglycerides comes mainly from
18. Glycerol released from adipose tissue by hydrolysis of triglycerides is mainly
- (A) Galactose
- (B) Sulphate
- (C) Sphingosine
- (D) Fatty acid
2. Niemann-Pick disease results from deficiency of
- (A) Ceramidase
- (B) Sphingomyelinase
- (C) Arylsulphatase A
- (D) Hexosaminidase A
3. Chylomicron remnants are catabolised in
- (A) Intestine
- (B) Adipose tissue
- (C) Liver
- (D) Liver and intestine
4. VLDL remnant may be converted into
- (A) VLDL
- (B) LDL
- (C) HDL
- (D) Chylomicrons
5. Receptors for chylomicron remnants are
- (A) Apo A specific
- (B) Apo B-48 specific
- (C) Apo C specific
- (D) Apo E specific
6. LDL receptor is specific for
- (A) Apo B-48 and Apo B 100
- (B) Apo B-48 and Apo E
- (C) Apo B-100 and Apo D
- (D) Apo B-100 and apo D
7. Nascent HDL of intestinal origin lacks
- (A) Apo A
- (B) Apo C
- (C) Apo E
- (D) Apo C and Apo E
8. HDL is synthesized in
- (A) Adipose tissue
- (B) Liver
- (C) Intestine
- (D) Liver and intestine
9. Nascent HDL of intestinal origin acquires Apo C and Apo E from
- (A) Chylomicrons
- (B) VLDL
- (C) LDL
- (D) HDL of the hepatic origin
10. Heparin releasable hepatic lipase converts
- (A) VLDL remnants into LDL
- (B) Nascent HDL into HDL
- (C) HDL2 into HDL3
- (D) HDL3 into HDL2
11. Activated lecithin cholesterol acyl transferase is essential for the conversion of
- (A) VLDL remnants into LDL
- (B) Nascent HDL into HDL
- (C) HDL2 into HDL3
- (D) HDL3 into HDL2
12. Fatty liver may be caused by
- (A) Deficiency of methionine
- (B) Puromycin
- (C) Chronic alcoholism
- (D) All of these
13. Alcohol dehydrogenase converts ethanol into
- (A) Acetyl CoA
- (B) Acetaldehyde
- (C) Acetate
- (D) CO2 and H2O
14. Lipids are stored in the body mainly in the form of
- (A) Phospholipids
- (B) Glycolipids
- (C) Triglycerides
- (D) Fatty acids
15. Lipid stores are mainly present in
- (A) Liver
- (B) Brain
- (C) Muscles
- (D) Adipose tissue
16. Glycerol is converted into glycerol-3- phosphate by
- (A) Thiokinase
- (B) Triokinase
- (C) Glycerol kinase
- (D) All of these
17. In adipose tissue, glycerol-3-phosphate required for the synthesis of triglycerides comes mainly from
- (A) Hydrolysis of pre-existing triglycerides
- (B) Hydrolysis of phospholipids
- (C) Dihydroxyacetone phosphate formed in glycolysis
- (D) Free glycerol
18. Glycerol released from adipose tissue by hydrolysis of triglycerides is mainly
- (A) Taken up by liver
- (B) Taken up by extrahepatic tissues
- (C) Reutilised in adipose tissue
- (D) Excreted from the body
19. Free glycerol cannot be used for triglyceride synthesis
in
20. Adipose tissue lacks
21. A digestive secretion that does not contain any digestive enzyme is
22. Saliva contains a lipase which acts on triglycerides having
23. Salivary lipase hydrolyses the ester bond at
24. Salivary lipase converts dietary triglycerides into
25. Pancreatic lipase requires for its activity:
26. Pancreatic lipase converts triacylglycerols into
27. Oxidation of fatty acids occurs
28. Activation of fatty acids requires all the following except
29. Mitochondrial thiokinase acts on
30. Carnitine is required for the transport of
31. Carnitine acylcarnitine translocase is present
32. Net ATP generation on complete oxidation of stearic acid is
33. Propionyl CoA formed oxidation of fatty acids having an odd number of carbon atoms is converted into
34. α-Oxidation of fatty acids occurs mainly in
- (A) Liver
- (B) Kidney
- (C) Intestine
- (D) Adipose tissue
20. Adipose tissue lacks
- (A) Hormone-sensitive lipase
- (B) Glycerol kinase
- (C) cAMP-dependent protein kinase
- (D) Glycerol-3-phosphate dehydrogenase
21. A digestive secretion that does not contain any digestive enzyme is
- (A) Saliva
- (B) Gastric juice
- (C) Pancreatic juice
- (D) Bile
22. Saliva contains a lipase which acts on triglycerides having
- (A) Short chain fatty acids
- (B) Medium chain fatty acids
- (C) Long chain fatty acids
- (D) All of these
23. Salivary lipase hydrolyses the ester bond at
- (A) Position 1 of triglycerides
- (B) Position 2 of triglycerides
- (C) Position 3 of triglycerides
- (D) All of these
24. Salivary lipase converts dietary triglycerides into
- (A) Diglycerides and fatty acids
- (B) Monoglycerides and fatty acids
- (C) Glycerol and fatty acids
- (D) All of these
25. Pancreatic lipase requires for its activity:
- (A) Co-lipase
- (B) Bile salts
- (C) Phospholipids
- (D) All of these
26. Pancreatic lipase converts triacylglycerols into
- (A) 2, 3-Diacylglycerol
- (B) 1-Monoacylglycerol
- (C) 2-Monoacylglycerol
- (D) 3-Monoacylglycerol
27. Oxidation of fatty acids occurs
- (A) In the cytosol
- (B) In the matrix of mitochondria
- (C) On inner mitochondrial membrane
- (D) On the microsomes
28. Activation of fatty acids requires all the following except
- (A) ATP
- (B) Coenzyme A
- (C) Thiokinase
- (D) Carnitine
29. Mitochondrial thiokinase acts on
- (A) Short chain of fatty acids
- (B) Medium chain fatty acids
- (C) Long chain fatty acids
- (D) All of these
30. Carnitine is required for the transport of
- (A) Triglycerides out of liver
- (B) Triglycerides into mitochondria
- (C) Short chain fatty acids into mitochondria
- (D) Long chain fatty acids into mitochondria
31. Carnitine acylcarnitine translocase is present
- (A) In the inner mitochondrial membrane
- (B) In the mitochondrial matrix
- (C) On the outer surface of inner mitochondrial membrane
- (D) On the inner surface of inner mitochondrial membrane
32. Net ATP generation on complete oxidation of stearic acid is
- (A) 129
- (B) 131
- (C) 146
- (D) 148
33. Propionyl CoA formed oxidation of fatty acids having an odd number of carbon atoms is converted into
- (A) Acetyl CoA
- (B) Acetoacetyl CoA
- (C) D-Methylmalonyl CoA
- (D) Butyryl CoA
34. α-Oxidation of fatty acids occurs mainly in
- (A) Liver
- (B) Brain
- (C) Muscles
- (D) Adipose tissue
35. Refsum’s disease results from a defect in the following
pathway except
36. The end product of omega-oxidation of fatty acids having an even number of carbon atoms is
37. De novo synthesis of fatty acids is catalysed by a multi-enzyme complex which contains
39. Fat depots are located in
40. Salivary lipase is secreted by
41. Co-lipase is a
42. Plasma becomes milky
43. Mitochondrial membrane is permeable to
44. During each cycle of β-oxidation
45. Net generation of energy on complete oxidation of palmitic acid is
46. Net generation of energy on complete oxidation of a 17-carbon fatty acid is
47. Net energy generation on complete oxidation of linoleic acid is
48. Extramitochondrial synthesis of fatty acids occurs in
49. One functional sub-unit of multi-enzyme complex for de novo synthesis of fatty acids contains
- (A) Alpha-oxidation of fatty acids
- (B) Beta-oxidation of fatty acids
- (C) Gamma-oxidation of fatty acids
- (D) Omega-oxidation of fatty acids
36. The end product of omega-oxidation of fatty acids having an even number of carbon atoms is
- (A) Adipic acid
- (B) Suberic acid
- (C) Both (A) and (B)
- (D) None of these
37. De novo synthesis of fatty acids is catalysed by a multi-enzyme complex which contains
- (A) One-SH group
- (B) Two-SH groups
- (C) Three-SH groups
- (D) Four-SH groups
39. Fat depots are located in
- (A) Intermuscular connective tissue
- (B) Mesentary
- (C) Omentum
- (D) All of these
40. Salivary lipase is secreted by
- (A) Parotid glands
- (B) Sub-maxillary glands
- (C) Dorsal surface of tongue
- (D) None of these
41. Co-lipase is a
- (A) Bile salt
- (B) Vitamin
- (C) Protein
- (D) Phospholipid
42. Plasma becomes milky
- (A) Due to high level of HDL
- (B) Due to high level of LDL
- (C) During fasting
- (D) After a meal
43. Mitochondrial membrane is permeable to
- (A) Short chain fatty acids
- (B) Medium chain fatty acids
- (C) Long chain fatty acids
- (D) All of these
44. During each cycle of β-oxidation
- (A) One carbon atom is removed from the carboxyl end of the fatty acid
- (B) One carbon atom is removed from the methyl end of the fatty acid
- (C) Two carbon atoms are removed from the carboxyl end of the fatty acid
- (D) Two carbon atoms are removed from the methyl end of the fatty acid
45. Net generation of energy on complete oxidation of palmitic acid is
- (A) 129 ATP equivalents
- (B) 131 ATP equivalents
- (C) 146 ATP equivalents
- (D) 148 ATP equivalents
46. Net generation of energy on complete oxidation of a 17-carbon fatty acid is
- (A) Equal to the energy generation from a 16-carbon fatty acid
- (B) Equal to the energy generation from an 18-carbon fatty acid
- (C) Less than the energy generation from a 16-carbon fatty acid
- (D) In between the energy generation from a 16-carbon fatty acid and an 18-carbon fatty acid
47. Net energy generation on complete oxidation of linoleic acid is
- (A) 148 ATP equivalents
- (B) 146 ATP equivalents
- (C) 144 ATP equivalents
- (D) 142 ATP equivalents
48. Extramitochondrial synthesis of fatty acids occurs in
- (A) Mammary glands
- (B) Lungs
- (C) Brain
- (D) All of these
49. One functional sub-unit of multi-enzyme complex for de novo synthesis of fatty acids contains
- (A) One —SH group
- (B) Two —SH groups
- (C) Three —SH groups
- (D) Four —SH groups
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