BIO CHEMISTRY MCQs (PART 2)

1. Proteins which are responsible for defence mechanism are called

(A) Antimetabolites

(B) Antibodies

(D) Apoproteins

2. When the net charge on an amino acid is zero, the pH is maintained as?

(A) 4.5

(B) 11.2

(D) 9.1

3. Isoelectric point of amino acids is used for

(A) Crystallisation

(B) Precipitation

(D) Reactivity

4. Xanthoproteic test is positive in proteins containing

(A) Sulphur amino acids

(B) α-Amino acids

(D) Aliphatic amino acids

5. All α-amino acids give positive

(A) Million’s test

(B) Biurete test

(D) Ninhydrine test

6. N-terminal amino acids of a polypeptide are estimated by

(A) Edmann reaction

(B) Sanger’s reagent

(D) Ninhydrine reaction

7. Million’s test is positive for

(A) Phenylalanine

(B) Glycine

(D) Proline

8. Indole group of tryptophan responses positively to

(A) Glyoxylic acid

(B) Schiff’s reagent

(D) Resorcinol test

9. Guanidine group of argentine gives positive test with

(A) Lead acetate

(B) Sakaguchi reagent

(D) Molisch’s reagent

10. Thiol group of cysteine gives red colour with

(A) Sodium acetate

(B) Lead acetate

(D) Barfoed’s reagent

11. Protein deficiency disease is known as

(A) Cushing’s disease

(B) Fabry’s disease

(D) Kwashiorkor and marasmus

12. A vegetable source of protein is

(A) Egg plant

(B) Soyabean

(D) Devil’s dung

13. Oxaloacetate is converted to aspartic acid by

(A) Reductase

(B) Oxidase

(D) Catalase

14. Deficiency of biotin results in decrease in

(A) Amino acid synthesis

(B) Lipid synthesis

(D) Fatty acid synthesis

15. The precursor of bile salts, sex hormones and vitamin D is

(A) Diosgenin

(B) Cholesterol

(D) Ergosterol

16 Unsaturated fatty acids is known as

(A) Non-essential fatty acids

(B) Essential fatty acids

(D) Phospholipids

17 Biuret test is specific for

(A) Two peptide linkage

(B) Phenolic group

(D) None of these

18. Most of calcium is present in bone, but 2% present in soft tissue and the blood is called

(A) Calcinated blood

(B) Solidified blood

(D) Colloidal blood

19. Calcium present with protein is known as free while in salt form is called as

(A) Bound

(B) Precipitated

(D) Polymorphs

20. The following ions help in enzymatic transfer of phosphate from ATP to pyruvic acid:

(A) Sodium

(B) Calcium

(D) Potassium

21. International enzyme commission classifies enzymes into

(A) Three classes

(B) Six classes

(D) Ten classes

22. Michaelis – Menten equation is used to explain the effect of substrate concentration on

(A) Carbohydrate

(B) Enzyme

(D) Protein

23. The pH at which an enzyme has maximum activity is known as

(A) Isoelectric pH

(B) Optimum Ph

(D) High pH

24. Degradation of proteins to amino acids, glucose from carbohydrates and fatty acids from lipids is known as

(A) Anabolism

(B) Metabolism

(D) Cretinism

25. During glycolysis of glucose the energy liberated in the absence of oxygen is known as

(A) Oxygenesis

(B) Glyconeogenesis

(D) Anaerobic fermentation

26. Deficiency of urea cycle enzymes results into accumulation of citrulline argininosuccinate arginine in the liver resulting in increasing concentration of …….. in the blood.

(A) Calcium

(B) Sodium

(D) Lipid

27. Accumulation of trytophan in blood is known as

(A) Pompe’s disease

(B) Wilson’s disease

(D) Hartnup’s disease

28. Lymphocytes are responsible for the formation of

(A) Serum

(B) Plasma

(D) Calcium

29. Platelets contain an enzyme which has important role in clotting in blood. This enzyme is known as (A) Cholinesterase

(B) Transaminase

(D) Thrombokinase

30. Treatment of pentoses with a concentrated mineral acid yields a cyclic aldehyde known as

(A) Pentaldehyde

(B) Cyclopental

(D) Furfural

31. Isoelectric pH is that pH at which protein is electrically:

(A) Neutral

(B) Anionic

(D) None of these

32. About 6.25 g of haemoglobin is produced and destroyed in the body each day and the total amount of haemoglobin in a normal healthy 70 kg weighing male adult is

(A) 250 g

(B) 150 g

(D) 70 g

33. Pancreatic juice contains all of the following except

(A) Trypsinogen

(B) Lipase

(D) Chymnotrypsinogen

34. The milk protein in the stomach in an adult is digested by

(A) Pepsin

(B) Rennin

(D) Chymotrypsinogen

35. Carboxypeptidase, an enzyme of pancreatic juice, contains

(A) Mn (B) Zinc

(D) Manganese

36. The zymogen from trypsinogen of pancreatic juice is converted to active trypsin by

(A) Peisin

(B) Enterocrinin

(D) Rennin

37. Inactive zymogens are precursors of all the following gastrointestinal enzymes except

(A) Carboxypeptidase

(B) Pepsin

(D) Chymotrypsin

38. Rennin acts on casein of milk in infants in presence of

(A) Mg++

(B) Zn++

(D) Ca++

39. All the following are true about phenylketonuria except

(A) Deficiency of phenylalanine hydroxylase

(B) Mental retardation

(D) Decrease serotonin formation

40. Which of the amino acid produces a vasodilator on decarboxylation?

(A) Glutamin acid

(B) Histidine

(D) Cysteine

41. Neutral amino acid is

(A) Leucine

(B) Lysine

(D) Histidine

42. The amino acid containing hydroxy group:

(A) Glycine

(B) Isoleucine

(D) Thereonine

43. The amino acid which synthesizes many hormornes:

(A) Valine

(B) Phenylalanine

(D) Histidine

44. Insulin degradation of disulfide bond formation is effected by

(A) Pyruvate dehydrogenase

(B) Xylitol reductase

(D) Xanthine oxidase

45. A protein reacts with biuret reagent which indicates 2 or more

(A) Blood clotting

(B) Peptide bond

(D) Hydrophobic bonds

46. In many proteins the hydrogen bonding produces a regular coiled arrangement which is called as (A) β-Helix

(B) α-Helix

(D) Spiral

47. The milk protein in the stomach of the infants is digested by

(A) Pepsin

(B) Trypsin

(D) Rennin

48. Protein anabolism is stimulated by

(A) ACTH

(B) Testosterone

(D) Epinephrine

49. The number of helices present in a collagen molecule is

(A) 1

(B) 2

(D) 4

50. Which bond is present in the primary structure of protein?

(A) Ester

(B) Hydrogen

(D) Peptide

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BIO CHEMISTRY MCQs (PART 2)