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Chemistry MCQs

Chemistry MCQs 












00. Serum lipase is increased in
(A) Acute parotitis
(B) Acute pancreatitis
(C) Infective hepatitis
(D) Biliary obstruction

01. Which one of the following metabolites is not directly produced in the hexose monophosphate pathway?
(A) Fructose-6-phosphate
(B) Dihydroxy acetone phosphate
(C) CO2
(D) Erythrose-4-phosphate

02. Which one of the following statements concerning glucose-6-phosphate dehydrogenase deficiency is correct?
(A) Young R.B.Cs, particularly reticulocytes, contain the highest enzyme activity cells show less enzyme activity
(B) Glucose-6-P Dehydroglucose deficiency leads to disfuction of many tissues
(C) G-6-p Dehydroglucose deficiency is due to a single deletion of a large sequence of DNA in the G-6-PD gene
(D) G-6-PD deficiency is precipitated by ingestion of drugs such as aspirin

03. The phenomenon of inhibition of glycolysis by O2 is termed as
(A) Red drop
(B) Pasteur effect
(C) Michaelis effect
(D) Fischer’s effect

04. Seratonin is derived in the body from the following amino acid:
(A) Phenylalanine
(B) Histidine
(C) Tryptophan
(D) Serine

05. Which amino acid is a lipotropic factor?
(A) Lysine
(B) Leucine
(C) Tryptophan
(D) Methionine


06. Which among the following is a nutritionally essential amino acid for man ?
(A) Alanine
(B) Glycine
(C) Tyrosine
(D) Tryptophan

07. The essential amino acids
(A) Must be supplied in the diet because the organism has lost the capacity to aminate the corresponding ketoacids
(B) Must be supplied in the diet because the human has an impaired ability to synthesize the carbon chain of the corresponding ketoacids
(C) Are identical in all species studied
 (D) Are defined as those amino acids which cannot be synthesized by the organism at a rate adequate to meet metabolic requirements

08. Which among the following is an essential amino acid?
(A) Cysteine
(B) Leucine
(C) Tyrosine
(D) Aspartic acid

09. Which among the following is a basic amino acid?
(A) Aspargine
(B) Arginine
(C) Proline
(D) Alanine

10. This amino acid cannot have optical isomers:
(A) Alanine
(B) Histidine
(C) Threonine
(D) Glycine


11. The amino acid which contains a guanidine group is
(A) Histidine
(B) Arginine
(C) Citrulline
(D) Ornithine

12. GABA(gama amino butyric acid) is
(A) Post-synaptic excitatory transmitter
(B) Post-synaptic inhibitor transmitter
(C) activator of glia-cell function
(D) inhibitor of glia-cell function

13. Sulphur-containing amino acid is
(A) Glutathione
(B) Chondroitin sulphate
(C) Homocysteine
(D) Tryptophan

14. The useful reagent for detection of amino acids is
(A) Molisch reagent
(B) Dichlorophenol Indophenol
(C) Ninhydrin
(D) Biuret

15. The amino acid which contains an indole group is
(A) Histidine
(B) Arginine
(C) Glycine
(D) Tryptophan



16. Sakaguchi reaction is answered by
(A) Lysine
(B) Ornithine
(C) Arginine
(D) Arginino succinic acid

17. The pH of an amino acid depends
(A) Optical rotation
(B) Dissociation constant
(C) Diffusion coefficient
(D) Chain length

18. When amino acids are treated with neutral formaldehyde, the pH of the mixture
(A) Is not altered
(B) Increases
(C) Decreases
(D) First increases then decreases

19. Which among the following has an imidazole group?
(A) Histidine
(B) Tryptophan
(C) Proline
(D) Hydroxy proline

 20. The amino acid exist as Zwitter ions when they are in
(A) solid state
(B) acidic solution
(C) alkaline solution
(D) neutral solution

21. Plasma proteins are isolated by
(A) Salting out
(B) Electrophoresis
(C) Flourimetry
(D) Both (A) and (B)



22. After digestion amino acids
(A) Are absorbed into portal circulation
(B) Are absorbed into lymph
(C) Are excreted to the extent of 50%
(D) Converted into glucose in the intestine

23. Cysteine has the formula:
(A) CH3SH
(B) H2N—CH2—COOH
(C) HS—CH2—CH(NH2)—COOH
(D) S—CH2—CH(NH2)—COOH | S—CH2—CH(NH2)—COOH

24. The compound having the formula H2N—CO—NH—CH2—CH2—CH2—CH— COOH is | NH2
(A) Lysine
(B) Glutamine
(C) Serine
(D) Citrulline

25. An amino acid which contains a disulphide bond is
(A) Lysine
 (B) Methionine
(C) Homocysteine
(D) Cystine



26. One of the following has a phenolic group:
 (A) Histidine
(B) Hydroxy lysine
(C) Seratonine
(D) Hydroxy proline

27. An amino acid not containing the usual— COOH group is
 (A) Alanine
(B) Tryptophan
(C) Methionine
(D) Taurine

28. Branched chain amino acids are
(A) Cysteine and cystine
(B) Tyrosine and Tryptophan
(C) Glycine and Serine
(D) Valine, Leucine and Isoleucine

29. A Zwitter ion is one which has in aqueous solution:
 (A) One positive charge and one negative charge
(B) Two positive charges and one negative charge
(C) Two negative charges and one positive charge
(D) No electrical charges at all



30. The amino acid which gives yellow colour with Ninhydrin in paper chromatography is
(A) Tyrosine
(B) Proline
(C) Tryptophan
(D) Alanine

31. Hydroxylation of Proline and Lysine in a protein is effected by
(A) Vitamin B1
(B) Vitamin B2
(C) Vitamin B6
(D) Vitamin C

32. Millon’s test is for identification of
(A) Tyrosine
(B) Tryptophan
(C) Proline
 (D) Arginine

33. Hopkins-Cole test is for identification of
 (A) Tyrosine
(B) Tryptophan
(C) Arginine
 (D) Cysteine



34. Collagen is very rich in
 (A) Glycine
(B) Serine
(C) Aspartic acid
(D) Glutamic acid

35. All amino acids are optically active except
(A) Glycine
(B) Serine
(C) Threonine
(D) Tryptophan

36. Out of 200 different amino acids form in nature the number of amino acids present in protein:
(A) 20
 (B) 25
(C) 40
(D) 35

37. Enzyme catalyzed hydrolysis of proteins produces amino acids of the form:
(A) D
(B) L
(C) DL
(D) All of these


38. The ionizable groups of amino acids are at least.
(A) 1
(B) 2
(C) 3
(D) 4

39. The neutral amino acid is
(A) Lysine
(B) Proline
(C) Leucine
(D) Histidine

40. The amino acid containing hydroxyl group:
 (A) Alanine
(B) Isoleucine
(C) Arginine
(D) Threonine

41. The sulphur containing amino acid:
(A) Homoserine
(B) Serine
(C) Methionine
(D) Valine

42. The basic amino acid:
(A) Glycine
(B) Leucine
(C) Histidine
(D) Proline

43. The amino acid which synthesizes many hormones:
(A) Valine
(B) Phenyl alanine
(C) Alanine

 (D) Histidine

44. Amino acids are insoluble in
(A) Acetic acid
(B) Chloroform
(C) Ethanol
(D) Benzene

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