Biology MCQs with Answer (part1) by General knowledge Solutions
Biology MCQs with Answer (part1) by General knowledge Solutions
1. Number of amino
acid residues in human growth hormone is
(A) 51
(B) 84
(C) 191
(D) 198
2. Number of amino acid residues in prolactin is
(A) 51
(B) 84
(C) 191
(D) 198
3. Secretion of
prolactin is regulated by
(A) Feedback inhibition
(B) Prolactin releasing hormone
(C) Prolactin release inhibiting hormone
(D) All of these
4. Precursor of ACTH
is
(A) Cholesterol
(B) Pregnenolone
(C) Corticotropin
(D) Pro-opiomelanocortin
5. All of the
following can be formed from pro-opiomelanocortin except
(A) α-and β-MSH
(B) β-and γ-Lipotropins
(C) α-and β-Endorphins
(D) FSH
6. All the following
statements about proopiomelanocortin are true except
(A) It is made up of 285 amino acids
(B) It is synthesised in pars intermedia and anterior lobe
of pituitary gland
(C) It is the precursor of ACTH and melatonin
(D) It is the precursor of corticotropin like intermediate lobe
peptide and endorphins
7. All the following
statements about ACTH are true except
(A) It is a tropic hormone
(B) Its target cells are located in adrenal cortex
(C) Its receptors are located in the cell membrane
(D) Its second messenger is inositol triphosphate
8. Regulation of ACTH
secretion occurs through
(A) Corticotropin releasing hormone (CRH) and corticotropin
release inhibiting hormone (CRIH) of hypothalamus
(B) Feedback inhibition by cortisol
(C) CRH and feedback inhibition by cortisol
(D) CRIH and feedback inhibition by cortisol
9. ACTH is a
polypeptide made up of
(A) 39 amino acids
(B) 41 amino acids
(C) 51 amino acids
(D) 84 amino acids
10. CRH is a
polypeptide made up of
(A) 39 amino acids
(B) 41 amino acids
(C) 51 amino acids
(D) 84 amino acids
11. Hormonal activity
of ACTH is completely lost on removal of
(A) 5 C-terminal amino acids
(B) 10 C-terminal amino acids
(C) 15 C-terminal amino acids
(D) None of these
12. All the following statements about TSH are true except
(A) It is a glycoprotein
(B) It is made up of α- and β-subunits
(C) Receptor recognition involves both the subunits
(D) Its subunit is identical with those of FSH and LH
13. All the following statements about TSH are true except
(A) It is a tropic hormone
(B) It acts on para-follicular cells of thyroid glands
(C) Its receptors are membrane-bound
(D) Its second messenger is cyclic AMP
14. All the following statements about thyrotropin releasing hormone
are true except
(A) It is secreted by hypothalamus
(B) It is a pentapeptide
(C) It increases the secretion of TSH
(D) Its secretion is inhibited by high level of T3 and T4 in
blood
15. In males,
luteinising hormone acts on
(A) Leydig cells
(B) Sertoli cells
(C) Prostate gland
(D) All of these
16. All the following
statements about FSH are true except
(A) It is a tropic hormone secreted by anterior pituitary
(B) Its secretion is increased by gonadotropin releasing
hormone
(C) It acts on Sertoli cells
(D) It increases the
synthesis of testosterone
17. In males,
secretion of luteinising hormone is inhibited by
(A) Gonadotropin releasing hormone
(B) FSH
(C) High blood level of testosterone
(D) Inhibin
18. Secretion of
luteinising hormone is increased by
(A) GnRH
(B) FSH
(C) Testosterone
(D) None of these
19. In structure and function, HCG resembles
(A) FSH
(B) LH
(C) GnRH
(D) Progesterone
20. Acromegaly results from overproduction of
(A) ACTH during childhood
(B) TSH during adult life
(C) Growth hormone during childhood
(D) Growth hormone during adult life
21. Acromegaly results
in all the following except
(A) Overgrowth of the bones of face, hands and feet
(B) Increased stature
(C) Enlargements of viscera
(D) Impaired glucose tolerance
22. Overproduction of
growth hormone during childhood causes
(A) Acromegaly
(B) Gigantism
(C) Cushing’s disease
(D) Simmond’s disease
23. Decreased
secretion of growth hormone during childhood causes
(A) Simmond’s disease
(B) Cushing’s disease
(C) Dwarfism
(D) Cretinism
24. Stature is
increased in
(A) Gigantism
(B) Acromegaly
(C) Simmond’s disease
(D) Cushing’s disease
25. An amino acid
used for the synthesis of thyroid hormone is
(A) Tyrosine
(B) Tryptophan
(C) Histidine
(D) Proline
26. An enzyme
required for the synthesis of thyroid hormones is
(A) Iodinase
(B) Deiodinase
(C) Thyroperoxidase
(D) Thyroxine synthetase
27. Thyroperoxidase
iodinates
(A) Free tyrosine in thyroid gland
(B) Tyrosine residues of thyroglobulin
(C) Tyrosine residues of thyroxine binding globulin
(D) Tyrosine residues of thyroxine binding prealbumin
28. In thyroxine,
tyrosine residues are iodinated at positions:
(A) 1 and 3
(B) 2 and 4
(C) 3 and 5
(D) 4 and 6
29. Thyroid gland
takes up circulating iodine
(A) By simple diffusion
(B) By facilitated diffusion
(C) By active uptake
(D) In exchange for chloride
30. Thyroid hormones
are present in blood
(A) In free form
(B) In association with thyroxine binding globulin (TBG)
(C) In association with thyroxine binding prealbumin (TBPA)
(D) Mainly in association with TBG, partly in free form and
sometimes in association with TBPA also
31. When thyroxine
binding globulin and thyroxine binding pre-albumin are saturated with
thyroxine, the excess hormone is transported by
(A) Albumin
(B) Gamma globulins
(C) Transcortin
(D) None of these
32. Receptors for
thyroid hormones are present
(A) On the cell membrane
(B) Across the cell membrane
(C) Inside the cells
(D) In association with G-proteins
33. Binding of
thyroxine to its receptors
(A) Activates Adenylate cyclase
(B) Activates guanylate cyclase
(C) Activates a stimulatory G-protein
(D) Increases transcription
34. The most powerful
thyroid hormone is
(A) Reverse T3
(B) DIT
(C) T3
(D) T4
35. The most abundant
thyroid hormone in blood is
(A) Free T3
(B) T3 bound to TBG
(C) Free T4
(D) T4 bound to TBG
36. Secretion of
thyroid hormones is regulated by
(A) Hypothalamus
(B) Anterior pituitary
(C) Feedback regulation
(D) All of these
1. C 2. D 3. C 4. D 5. D 6. C 7. D 8. C 9. A 10. B 11. D 12.
D 13. B 14. B 15. A 16. D 17. C 18. A 19. B 20. D 21. B 22. B 23. C 24. A 25. A
26. C 27. B 28. C 29. C 30. D 31. A 32. C 33. D 34. C 35. D 36. D
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