Biology MCQs with Answer (part 2) by General knowledge Solutions
Biology MCQs with Answer (part 2) by General knowledge Solutions
1. Melanogenesis is stimulated by
(A) MSH
(B) FSH
(C) LH
(D) HCG
2. The number of
amino acids in antidiuretic hormone is
(A) 9
(B) 18
(C) 27
(D) 36
3. ADH
(A) Reabsorbs water from renal tubules
(B) Excretes water from renal tubules
(C) Excretes hypotonic urine
(D) Causes low specific gravity of urine
4. Increased reabsorption of water from the kidney is the
major consequence of the secretion of the hormone?
(A) Cortisol
(B) Insulin
(C) Vasopressin
(D) Aldosterone
5. An increase in the osmolality of extracellular compartment will
(A) Inhibit ADH secretion
(B) Stimulate ADH secretion
(C) Cause no change in ADH secretion
(D) Stimulate the volume and osmoreceptor and inhibit ADH
secretion
6. For Catecholamine biosynthesis the rate limiting enzyme
is
(A) DOPA decarboxylase
(B) DOPAMINE β-hydroxylase
(C) Tyrosine hydroxylase
(D) Phenylalanine hydroxylase
7. A hormone which
cannot cross the blood brain barrier is
(A) Epinephrine
(B) Aldosterone
(C) ACTH
(D) TSH
8. The plasma level
of epinephrine is less than
(A) 0.1 ng/ml
(B) 0.2 ng/ml
(C) 0.4 ng/ml
(D) 0.8 ng/ml
9. Epinephrine is
rapidly metabolized by
(A) Monoamine oxidase
(B) Deaminase
(C) Transminase
(D) Decarboxylase
10. Pheochromocytomas
are tumours of
(A) Adrenal cortex
(B) Adrenal medulla
(C) Pancreas
(D) Bone
11. A characteristic
of pheochromocytoma is elevated urinary excretion of
(A) Dopamine
(B) Tyrosine
(C) Vinylmandelic acid
(D) Phenylalanine
12. In the synthetic pathway of epinephrine, disulfiram
(antabuse) inhibits the enzyme:
(A) Tyrosine hydroxylase
(B) Dopamine β-hydroxylase
(C) DOPA decarboxylase
(D) N-methyl transferase
13. The biosynthesis of both Catecholamine and serotonin
require
(A) Tyrosine hydroxylase (B) N-methyl transferase
(C) Aromatic amino acid decarboxylase
(D) Tryptophan pyrrolase
14. Epinephrine
stimulates glycogenolysis in
(A) Liver
(B) Muscle
(B) Muscle
(C) Liver and muscle
(D) Kidney
15. A cup of strong
coffee would be expected to
(A) Interfere with the synthesis of prostaglandins
(B) Decrease the effect of glucagon
(C) Enhance the effect of epinephrine
(D) Provide the vitamin nicotinic acid
16. Epinephrine is derived from norepinephrine by
(A) Decarboxylation
(B) Hydroxylation
(C) Oxidation
(D) N-methylation
17. 5 HIAA test is negative if patient is taking
(A) Aspirin
(B) Colchicine
(C) Phenothiazone
(D) Methotrexate
18. Presence of
significant amount of 5-HIAA in urine indicates
(A) Carcinoid in liver
(B) Carcinoid in appendix
(C) Metastasis of carcinoma of liver
(D) Hepatoma
19. The normal serum
level of triiodothyronine (T3) is
(A) 0.2–0.5 ng/ml
(B) 0.7–2.0 ng/ml
(C) 2.0–4.0 ng/ml
(D) 5.0–8.0 ng/ml
20. The normal serum level of thyroxine (T4) is
(A) 2.0–4.0 µg/100 ml
(B) 5.5–13.5 µg/100 ml
(C) 14.0–20.3 µg/100 ml
(D) 20.0–25.0 µg/100 ml
21. Excess secretion of thyroid hormones causes
(A) Hyperthyroidism
(B) Myxoedema
(C) Cretinism
(D) Cushing syndrome
22. Insufficient free
T3 and T4 results in
(A) Grave’s disease
(B) Mysoedema
(C) Cushing syndrome
(D) Gigantism
23. In primary
hypothyroidism the useful estimation is of
(A) T3
(B) T4
(C) TBG
(D) Autoantibodies
24. When iodine supplies are sufficient the T3 and T4 ratio
in thyroglobulin is
(A) 1 : 2
(B) 1 : 4
(C) 1 : 7
(D) 1 : 10
25. A substance which
competes with iodide uptake mechanism by thyroid gland is
(A) Thiocynate
(B) Iodoacetate
(C) Fluoride
(D) Fluoroacetate
26. Thyroperoxidase
enzyme contains
(A) Heme
(B) Copper
(C) Zinc
(D) Magnesium
27. Thyroproxidase requires hydrogen peroxide as oxidizing agent. The H2O2 is produced by (A) FADH2 dependent enzyme
(B) NADH dependent enzyme
(C) NADP dependent enzyme
(D) NADPH dependent enzyme
28. Thyroid stimulating hormone is a dimer. The α-subunits of TSH, LH, FSH are identical. Thus the biological specificity must therefore be β subunit in which the number of amino acids is
(A) 78
(B) 112
(C) 130
(D) 199
29. TSH stimulates the synthesis delete
(A) Thyroxine
(B) Adrenocorticoids
(C) Epinephrine
(D) Insulin
30. Thyroid hormones
are synthesized by the iodination of the amino acid:
(A) Glycine
(B) Phenylalanine
(C) Alanine
(D) Tyrosine
31. The tyrosine
residues per molecule of thyroglobulin is
(A) 85
(B) 95
(C) 115
(D) 135
32. The percentage of inactive precursors (monoidotyrosine and diiodotyrosine) in thyroglobulin is
(A) 30
(B) 40
(C) 50
(D) 70
33. The number of amino acids in parathormone is
(A) 65
(B) 84
(C) 115
(D) 122
34. The sequence of
amino acid in which the biological value of parathormone is
(A) 1–15
(B) 1–34
(C) 30–50
(D) 50–84
35. PTH
(A) Reduces the renal clearance or excretion of calcium
(B) Increases renal phosphate clearance
(C) Increases the renal clearance of calcium
(D) Decreases the renal phosphate clearance
36. The number of amino acids in the peptide hormone
calcitonin is
(A) 16
(B) 24
(C) 32
(D) 40
37. Calcitonin causes
(A) Calcinuria and phosphaturia
(B) Decrease in urinary calcium
(C) Decrease in urinary phosphorous
(D) Increase in blood calcium level
38. The characteristic of hyperparathyroidism is
(A) Low serum calcium
(B) High serum phosphorous
(C) Low serum calcium and high serum phosphorous
(D) High serum calcium and low serum phosphate
39. Parathyroid
hormone
(A) Is released when serum Ca++ is too high
(B) Inactivates vitamin D
(C) Is secreted when Ca++ is too low
(D) Depends on vitamin K for adequate activity
40. δ-Cells of islet of langerhans of pancreas produce
(A) Pancreatic polypeptide
(B) Pancreatic lipase
(C) Somatostatin
(D) Steapsin
41. β-cells of islet of langerhans of the pancreas secrete
(A) Insulin
(B) Glucagon
(C) Somatostatin
(D) Pancreatic polypeptide
42. Target tissue of insulin is
(A) Red blood cells
(B) Renal tubular cells
(C) GI tract epithelial cells
(D) Liver
Answer:
1. A 2. A 3. A 4. C 5. B 6. C 7. A 8. A 9. A 10. B 11. C 12.
B 13. B 14. C 15. C 16. D 17. C 18. C 19. B 20. B 21. A 22. B 23. D 24. C 25. A
26. A 27. D 28. B 29. A 30. D 31. C 32. D 33. B 34. B 35. A 36. C 37. A 38. D 39.
C 40. C 41. A 42. D
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