Free Bio Chemistry MCQs with Answer
Free Bio Chemistry MCQs with Answer
1. At a pH below the isoelectric point, an amino acid
exists as
(A) Cation
(B) Anion
(C) Zwitterion
(D) Undissociated molecule
2. An amino acid having a hydrophilic side chain is
(A) Alanine
(B) Proline
(C) Methionine
(D) Serine
3. An amino acid that does not take part in α helix formation is
(A) Histidine
(B) Tyrosine
(C) Proline
(D) Tryptophan
4. A protein rich in cysteine is
(A) Collagen
(B) Keratin
(C) Haemoglobin
(D) Gelatin
5. Primary structure of proteins can be determined by the use of
(A) Electrophoresis
(B) Chromatography
(C) Ninhydrin
(D) Sanger’s reagent
6. Electrostatic bonds can be formed between the side chains of
(A) Alanine and leucine
(B) Leucine and valine
(C) Asparate and glutamate
(D) Lysine and aspartate
7. Sanger’s reagent contains
(A) Phenylisothiocyanate
(B) Dansyl chloride
(C) 1-Fluoro-2, 4-dinitrobenzene
(D) Ninhydrin
8. The most abundant protein in mammals is
(A) Albumin
(B) Haemoglobin
(C) Collagen
(D) Elastin
9. Folding of newly synthesized proteins is accelerated by
(A) Protein disulphide isomerase
(B) Prolyl cis-trans isomerase
(C) Chaperonins
(D) All of these
10. Primary structure of a protein is formed by
(A) Hydrogen bonds
(B) Peptide bonds
(C) Disulphide bonds
(D) All of these
11. α-Helix is formed by
(A) Hydrogen bonds
(B) Hydrophobic bonds
(C) Electrostatic bonds
(D) Disulphide bonds
12. Glutelins are present in
(A) Milk
(B) Eggs
(C) Meat
(D) Cereals
13. Aromatic amino acids can be detected by
(A) Sakaguchi reaction
(B) Millon-Nasse reaction
(C) Hopkins-Cole reaction
(D) Xanthoproteic reaction
14. Two amino groups are present in
(A) Leucine
(B) Glutamate
(C) Lysine
(D) Threonine
15. During denaturation of proteins, all of the following are disrupted except
(A) Primary structure
(B) Secondary structure
(C) Tertiary structure
(D) Quaternary structure
16. All the following are branched chain amino acids except
(A) Isoleucine
(B) Alanine
(C) Leucine
(D) Valine
17. An –OH group is present in the side chain of
(A) Serine
(B) Arginine
(C) Lysine
(D) Proline
18. Edman’s reagent contains
(A) Phenylisothiocyanate
(B) 1-Fluoro-2, 4-dinitrobenzene
(C) Dansyl Chloride
(D) tBOC azide
(A) Cation
(B) Anion
(C) Zwitterion
(D) Undissociated molecule
2. An amino acid having a hydrophilic side chain is
(A) Alanine
(B) Proline
(C) Methionine
(D) Serine
3. An amino acid that does not take part in α helix formation is
(A) Histidine
(B) Tyrosine
(C) Proline
(D) Tryptophan
4. A protein rich in cysteine is
(A) Collagen
(B) Keratin
(C) Haemoglobin
(D) Gelatin
5. Primary structure of proteins can be determined by the use of
(A) Electrophoresis
(B) Chromatography
(C) Ninhydrin
(D) Sanger’s reagent
6. Electrostatic bonds can be formed between the side chains of
(A) Alanine and leucine
(B) Leucine and valine
(C) Asparate and glutamate
(D) Lysine and aspartate
7. Sanger’s reagent contains
(A) Phenylisothiocyanate
(B) Dansyl chloride
(C) 1-Fluoro-2, 4-dinitrobenzene
(D) Ninhydrin
8. The most abundant protein in mammals is
(A) Albumin
(B) Haemoglobin
(C) Collagen
(D) Elastin
9. Folding of newly synthesized proteins is accelerated by
(A) Protein disulphide isomerase
(B) Prolyl cis-trans isomerase
(C) Chaperonins
(D) All of these
10. Primary structure of a protein is formed by
(A) Hydrogen bonds
(B) Peptide bonds
(C) Disulphide bonds
(D) All of these
11. α-Helix is formed by
(A) Hydrogen bonds
(B) Hydrophobic bonds
(C) Electrostatic bonds
(D) Disulphide bonds
12. Glutelins are present in
(A) Milk
(B) Eggs
(C) Meat
(D) Cereals
13. Aromatic amino acids can be detected by
(A) Sakaguchi reaction
(B) Millon-Nasse reaction
(C) Hopkins-Cole reaction
(D) Xanthoproteic reaction
14. Two amino groups are present in
(A) Leucine
(B) Glutamate
(C) Lysine
(D) Threonine
15. During denaturation of proteins, all of the following are disrupted except
(A) Primary structure
(B) Secondary structure
(C) Tertiary structure
(D) Quaternary structure
16. All the following are branched chain amino acids except
(A) Isoleucine
(B) Alanine
(C) Leucine
(D) Valine
17. An –OH group is present in the side chain of
(A) Serine
(B) Arginine
(C) Lysine
(D) Proline
18. Edman’s reagent contains
(A) Phenylisothiocyanate
(B) 1-Fluoro-2, 4-dinitrobenzene
(C) Dansyl Chloride
(D) tBOC azide
19. Edman’s reaction can be used to
(A) Determine the number of tyrosine residues in a protein
(B) Determine the number of aromatic amino acid residues in a protein
(C) Determine the amino acid sequence of a protein
(D) Hydrolyse the peptide bonds in a protein
20. Inherited deficiency of β−glucosidase causes
(A) Tay-Sachs disease
(B) Metachromatic leukodystrophy
(C) Gaucher’s disease
(D) Multiple sclerosis
21. Tay-Sachs disease results from inherited deficiency of
(A) Arylsulphatase A
(B) Hexosaminidase A
(C) Sphingomyelinase
(D) Ceramidase
22. The largest alpolipoprotein is
(A) Apo E
(B) Apo B-48
(C) Apo B-100
(D) Apo A-I
23. Apolipoprotein B-100 is synthesised in
(A) Adipose tissue
(B) Liver
(C) Intestine
(D) Liver and intestine
24. Apolipoprotein B-48 is synthesized in
(A) Adipose tissue
(B) Liver
(C) Intestine
(D) Liver and intestine
25. Apolipoproteins A-I and A-II are present in
(A) LDL only
(B) LDL and VLDL
(C) HDL only
(D) HDL and chylomicrons
26. Apolipoprotein B-48 is present in
(A) Chylomicrons
(B) VLDL
(C) LDL
(D) HDL
27. Apolipoprotein B-100 is present in
(A) Chylomicrons
(B) VLDL only
(C) LDL only
(D) VLDL and LDL
28. Apolipoproteins C-I, C-II and C-III are present in
(A) Chylomicrons
(B) VLDL
(C) HDL
(D) All of these
29. Apolipoprotiens C-I, C-II and C-III are present in all of the following except
(A) Chylomicrons
(B) VLDL
(C) LDL
(D) HDL
30. Apolipoprotein A-I acts as
(A) Enzyme activator
(B) Ligand for receptor
(C) Both (A) and (B)
(D) None of these
31. Apolipoprotien B-100 acts as
(A) Enzyme activator
(B) Ligand for receptor
(C) Both (A) and (B)
(D) None of these
32. Apolipoprotein C-II is an activator of
(A) Lecithin cholesterola acyl transferase
(B) Phospholipase C
(C) Extrahepatic lipoprotein lipase
(D) Hepatic lipoprotein lipase
33. Nascent chylomicron receives apolipoproteins C and E from
(A) VLDL remnant
(B) VLDL
(C) LDL
(D) HDL
34. Terminal transferase
(A) Removes nucleotides from 3’ end
(B) Adds nucleotides at 3’ end
(C) Removes nucleotides from 3’end
(D) Adds nucleotides at 3’end
35. S1 nuclease hydrolyses
(A) DNA of somatic cells
(B) DNA of sperms
(C) Any double stranded DNA
(D) Any single stranded DNA
36. Positive nitrogen balance is seen in
(A) Starvation
(B) Wasting diseases
(C) Growing age
(D) Intestinal malabsorption
(A) Determine the number of tyrosine residues in a protein
(B) Determine the number of aromatic amino acid residues in a protein
(C) Determine the amino acid sequence of a protein
(D) Hydrolyse the peptide bonds in a protein
20. Inherited deficiency of β−glucosidase causes
(A) Tay-Sachs disease
(B) Metachromatic leukodystrophy
(C) Gaucher’s disease
(D) Multiple sclerosis
21. Tay-Sachs disease results from inherited deficiency of
(A) Arylsulphatase A
(B) Hexosaminidase A
(C) Sphingomyelinase
(D) Ceramidase
22. The largest alpolipoprotein is
(A) Apo E
(B) Apo B-48
(C) Apo B-100
(D) Apo A-I
23. Apolipoprotein B-100 is synthesised in
(A) Adipose tissue
(B) Liver
(C) Intestine
(D) Liver and intestine
24. Apolipoprotein B-48 is synthesized in
(A) Adipose tissue
(B) Liver
(C) Intestine
(D) Liver and intestine
25. Apolipoproteins A-I and A-II are present in
(A) LDL only
(B) LDL and VLDL
(C) HDL only
(D) HDL and chylomicrons
26. Apolipoprotein B-48 is present in
(A) Chylomicrons
(B) VLDL
(C) LDL
(D) HDL
27. Apolipoprotein B-100 is present in
(A) Chylomicrons
(B) VLDL only
(C) LDL only
(D) VLDL and LDL
28. Apolipoproteins C-I, C-II and C-III are present in
(A) Chylomicrons
(B) VLDL
(C) HDL
(D) All of these
29. Apolipoprotiens C-I, C-II and C-III are present in all of the following except
(A) Chylomicrons
(B) VLDL
(C) LDL
(D) HDL
30. Apolipoprotein A-I acts as
(A) Enzyme activator
(B) Ligand for receptor
(C) Both (A) and (B)
(D) None of these
31. Apolipoprotien B-100 acts as
(A) Enzyme activator
(B) Ligand for receptor
(C) Both (A) and (B)
(D) None of these
32. Apolipoprotein C-II is an activator of
(A) Lecithin cholesterola acyl transferase
(B) Phospholipase C
(C) Extrahepatic lipoprotein lipase
(D) Hepatic lipoprotein lipase
33. Nascent chylomicron receives apolipoproteins C and E from
(A) VLDL remnant
(B) VLDL
(C) LDL
(D) HDL
34. Terminal transferase
(A) Removes nucleotides from 3’ end
(B) Adds nucleotides at 3’ end
(C) Removes nucleotides from 3’end
(D) Adds nucleotides at 3’end
35. S1 nuclease hydrolyses
(A) DNA of somatic cells
(B) DNA of sperms
(C) Any double stranded DNA
(D) Any single stranded DNA
36. Positive nitrogen balance is seen in
(A) Starvation
(B) Wasting diseases
(C) Growing age
(D) Intestinal malabsorption
37. Alanine can be synthesized from
(A) Glutamate and α-ketoglutarate
(B) Pyruvate and glutamate
(C) Pyruvate and α-ketoglutarate
(D) Asparate and α-ketoglutarate
38. All of the following are required for synthesis of alanine except
(A) Pyruvate
(B) α-ketoglutarate
(C) Glutamate
(D) Pyridoxal phosphate
39. All of the following statements about aspartate are true except
(A) It is non-essential amino acid
(B) It is a dicarboxylic amino acid
(C) It can be synthesized from pyruvate and glutamate
(D) It can be converted into asparagine
40. Glycine can be synthesized from
(A) Serine
(B) Choline
(C) Betaine
(D) All of these
41. All of the following are required for synthesis of glutamine except
(A) Glutamate
(B) Ammonia
(C) Pyridoxal phosphate
(D) ATP
42. A coenzyme required for the synthesis of glycine from serine is
(A) ATP
(B) Pyridoxal phosphate
(C) Tetrahydrofolate
(D) NAD
43. All of the following statements about proline are true except
(A) It is an imino acid
(B) It can be synthesized from glutamate
(C) It can be catabolised to glutamate
(D) Free proline can be hydroxylated to hydroxyproline
44. A protein rich in hydroxyproline is
(A) Prolamin
(B) Procollagen
(C) Collagen
(D) Proinsulin
(A) Glutamate and α-ketoglutarate
(B) Pyruvate and glutamate
(C) Pyruvate and α-ketoglutarate
(D) Asparate and α-ketoglutarate
38. All of the following are required for synthesis of alanine except
(A) Pyruvate
(B) α-ketoglutarate
(C) Glutamate
(D) Pyridoxal phosphate
39. All of the following statements about aspartate are true except
(A) It is non-essential amino acid
(B) It is a dicarboxylic amino acid
(C) It can be synthesized from pyruvate and glutamate
(D) It can be converted into asparagine
40. Glycine can be synthesized from
(A) Serine
(B) Choline
(C) Betaine
(D) All of these
41. All of the following are required for synthesis of glutamine except
(A) Glutamate
(B) Ammonia
(C) Pyridoxal phosphate
(D) ATP
42. A coenzyme required for the synthesis of glycine from serine is
(A) ATP
(B) Pyridoxal phosphate
(C) Tetrahydrofolate
(D) NAD
43. All of the following statements about proline are true except
(A) It is an imino acid
(B) It can be synthesized from glutamate
(C) It can be catabolised to glutamate
(D) Free proline can be hydroxylated to hydroxyproline
44. A protein rich in hydroxyproline is
(A) Prolamin
(B) Procollagen
(C) Collagen
(D) Proinsulin
45. All the following statement about hydroxyproline are true except
(A) There is no codon for hydroxyproline
(B) It is present in large amounts in collagen
(C) Free proline cannot be hydroxylated to hydroxyproline
(D) Hydroxylation of proline residues is catalysed by a dioxygenase
46. All of the following are required for hydroxylation of proline residues except
(A) Ascorbic acid
(B) Glutamate
(C) Ferrous ions
(D) Molecular oxygen
47. Cysteine can be synthesized from methionine and
(A) Serine
(B) Homoserine
(C) Homocysteine
(D) Threonine
48. Methionine is synthesized in human body from
(A) Cysteine and homoserine
(B) Homocysteine and serine
(C) Cysteine and serine
(D) None of these
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