Biology MCQs with Answer by General knowledge Solutions
Biology MCQs with Answer by General knowledge Solutions
1. Cocarboxylase is
(A) Thiamine pyrophosphate
(B) Pyridoxal phosphate
(C) Biotin
(D) CoA
2. A coenzyme containing non aromatic hetero
ring is
(A) ATP
(B) NAD
(C) FMN
(D) Biotin
3. A coenzyme containing aromatic hetero ring
is
(A) TPP
(B) Lipoic acid
(C) Coenzyme Q
(D) Biotin
4. Isoenzymes are
(A) Chemically, immunologically and electrophoretically
different forms of an enzyme
(B) Different forms of an enzyme similar in all properties
(C) Catalysing different reactions
(D) Having the same
quaternary structures like the enzymes
5. Isoenzymes can be
characterized by
(A) Proteins lacking enzymatic activity that are necessary
for the activation of enzymes
(B) Proteolytic enzymes activated by hydrolysis
(C) Enzymes with
identical primary structure
(D) Similar enzymes that catalyse different reaction
6. The isoenzymes of
LDH
(A) Differ only in a single amino acid
(B) Differ in catalytic activity
(C) Exist in 5 forms depending on M and H monomer contents
(D) Occur as monomers
7. The normal value of CPK in serum varies
between
(A) 4–60 IU/L
(B) 60–250 IU/L
(C) 4–17 IU/L
(D) > 350 IU/L
8. Factors affecting
enzyme activity:
(A) Concentration
(B) pH
(C) Temperature
(D) All of these
9. The normal serum GOT activity ranges from
(A) 3.0–15.0 IU/L
(B) 4.0–17.0 IU/L
(C) 4.0–60.0 IU/L
(D) 0.9–4.0 IU/L
10. The normal GPT
activity ranges from
(A) 60.0–250.0 IU/L
(B) 4.0–17.0 IU/L
(C) 3.0–15.0 IU/L
(D) 0.1–14.0 IU/L
11. The normal serum acid phosphatase activity
ranges from
(A) 5.0–13.0 KA units/100 ml
(B) 1.0–5.0 KA units/100 ml
(C) 13.0–18.0 KA units/100 ml
(D) 0.2–0.8 KA units/100 ml
12. The normal serum
alkaline phosphatase activity ranges from
(A) 1.0–5.0 KA units/100 ml
(B) 5.0–13.0 KA units/100 ml
(C) 0.8–2.3 KA units/100 ml
(D) 13.0–21.0 KA units/100 ml
13. In early stages
of myocardial ischemia the most sensitive indicator is the measurement of the
activity of
(A) CPK
(B) SGPT
(C) SGOT
(D) LDH
14. Serum acid phosphatase level increases in
(A) Metastatic carcinoma of prostate
(B) Myocardial infarction
(C) Wilson’s disease
(D) Liver diseases
15. Serum a lka l ine
phosphatase leve l increases in
(A) Hypothyroidism
(B) Carcinoma of prostate
(C) Hyperparathyroidism
(D) Myocardial ischemia
16. Serum lipase level increases in
(A) Paget’s disease
(B) Gaucher’s disease
(C) Acute pancreatitis
(D) Diabetes mellitus
17. Serum ferroxidase level decreases in
(A) Gaucher’s disease
(B) Cirrhosis of liver
(C) Acute pancreatitis
(D) Wilson’s disease
18. The isoenzymes
LDH5 is elevated in
(A) Myocardial infarction
(B) Peptic ulcer
(C) Liver disease
(D) Infectious
diseases
19. On the third day of onset of acute
myocardial infarction the enzyme elevated is
(A) Serum AST
(B) Serum CK
(C) Serum LDH
(D) Serum ALT
20. LDH1 and LDH2 are elevated in
(A) Myocardial infarction
(B) Liver disease
(C) Kidney disease
(D) Brain disease
21. The CK isoenzymes present in cardiac
muscle is
(A) BB and MB
(B) MM and MB
(C) BB only
(D) MB only
22. In acute pancreatitis, the enzyme raised
in first five days is
(A) Serum amylase
(B) Serum lactic dehydrogenase
(C) Urinary lipase
(D) Urinary amylase
23. Acute
pancreatitis is characterised by
(A) Lack of synthesis
of zymogen enzymes
(B) Continuous release of zymogen enzymes into the gut
(C) Premature activation of zymogen enzymes
(D) Inactivation of zymogen enzymes
24. An example of functional plasma enzyme is
(A) Lipoprotein lipase
(B) Amylase
(C) Aminotransferase
(D) Lactate
dehydrogenase
25. A non-functional plasma enzyme is
(A) Psudocholinesterase
(B) Lipoprotein lipase
(C) Proenzyme of blood coagulation
(D) Lipase
26. The pH optima for salivary analyse is
(A) 6.6–6.8
(B) 2.0–7.5
(C) 7.9
(D) 8.6
27. The pH optima for
pancreatic analyse is
(A) 4.0
(B) 7.1
(C) 7.9
(D) 8.6
28. The pH optima for
sucrase is
(A) 5.0–7.0
(B) 5.8–6.2
(C) 5.4–6.0
(D) 8.6
29. The pH optima for
maltase is
(A) 1.0–2.0
(B) 5.2–6.0
(C) 5.8–6.2
(D) 5.4–6.0
30. The pH optima for
lactase is
(A) 1.0-2.0
(B) 5.4–6.0
(C) 5.0–7.0
(D) 5.8–6.2
31. The substrate for amylase is
(A) Cane sugar
(B) Starch
(C) Lactose
(D) Ribose
32. The ion which
activates salivary amylase activity is
(A) Chloride
(B) Bicarbonate
(C) Sodium
(D) Potassium
33. The pancreatic amylase activity is
increased in the presence of
(A) Hydrochloric acid
(B) Bile salts
(C) Thiocyanate ions
(D) Calcium ions
34. A carbohydrate
which can not be digested in human gut is
(A) Cellulose
(B) Starch
(C) Glycogen
(D) Maltose
35. The sugar
absorbed by fac i l itated diffusion and requiring Na independent transporter
is
(A) Glucose
(B) Fructose
(C) Galactose
(D) Ribose
36. In the intestine the rate of absorption is
highest for
(A) Glucose and galactose
(B) Fructose and mannose
(C) Fructose and pentose
(D) Mannose and pentose
37. Glucose
absorption is promoted by
(A) Vitamin A
(B) Thiamin
(C) Vitamin C
(D) Vitamin K
38. The harmone acting directly on intestinal
mucosa and stimulating glucose absorption is
(A) Insulin
(B) Glucagon
(C) Thyroxine
(D) Vasopressin
39. Given that the
standard free energy change (∆G°) for the hydrolysis of ATP is –7.3 K cal/mol
and that for the hydrolysis of Glucose 6-phosphate is –3.3 Kcal/mol, the ∆G°
for the phosphorylation of glucose is Glucose + ATP → Glucose 6– Phosphate +
ADP.
(A) –10.6 Kcal/mol
(B) –7.3 Kcal/mol
(C) –4.0 Kcal/mol
(D) +4.0 Kcal/mol
40. At low blood glucose concentration, brain
but not liver will take up glucose. It is due to the
(A) Low Km of hexokinase
(B) Low Km of glucokinase
(C) Specificity of glucokinase
(D) Blood brain barrier
41. In the reaction below, Nu TP stands for
NuTP + glucose → Glucose 6–Phosphate + NuDP.
(A) ATP
(B) CTP
(C) GTP
(D) UTP
42. In the figures shown below, fructose 1,6-
biphosphate is located at point:
(A) A
(B) B
(C) C
(D) D
Answers:
1. C 2. D 3. A 4 A 5. B 6. C 7. A 8. D 9. B 10. C 11. B 12.
B 13. A 14. A 15. C 16. C 17. D 18. C 19. C 20. A 21. B 22. A 23. C 24. A 25. D
26. A 27. D 28. A 29. C 30. B 31. B 32. A 33. B 34. A 35. B 36. A 37. B 38. C
39. C 40. A 41. A 42. C
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