Biochemistry MCQs
Biochemistry MCQs
256. The immunoglobulin having the longest half-life is
(A) IgA
(B) IgG
(C) IgM
(D) IgE
257. The half-life of IgG is
(A) 2–3 days
(B) 5–6 days
(C) 8–10 days
(D) 20–25 days
258. Recognition of antigen is the function of
(A) Variable region of light chains
(B) Variable regions of light and heavy chains
(C) Constant region of heavy chains
(D) Constant regions of light and heavy chains
259. The effector function of antibody is performed by
(A) Variable region of light chains
(B) Constant region of heavy chains
(C) Variable regions of light and heavy chains
(D) Constant regions of light and heavy chains
260. Complement system can be activated by binding of antigen to
(A) IgA
(B) IgD
(C) IgE
(D) IgM
261. C1 component of classical complement pathway is made up of
(A) Complements 1q and 1r
(B) Complements 1q and 1s
(C) Complements 1r and 1s
(D) Complements 1q, 1r and 1s
262. The components of complement system are activated by
(A) Microsomal hydroxylation
(B) Phosphorylation
(C) Glycosylation
(D) Proteloysis
263. The component system forms a membrane attack complex made up of
(A) Complements 1q, 1r and 1s
(B) Complements 1, 2, 3 and 4
(C) Complements 5b, 6, 7 and 8
(D) Factors B and D
(A) IgA
(B) IgG
(C) IgM
(D) IgE
257. The half-life of IgG is
(A) 2–3 days
(B) 5–6 days
(C) 8–10 days
(D) 20–25 days
258. Recognition of antigen is the function of
(A) Variable region of light chains
(B) Variable regions of light and heavy chains
(C) Constant region of heavy chains
(D) Constant regions of light and heavy chains
259. The effector function of antibody is performed by
(A) Variable region of light chains
(B) Constant region of heavy chains
(C) Variable regions of light and heavy chains
(D) Constant regions of light and heavy chains
260. Complement system can be activated by binding of antigen to
(A) IgA
(B) IgD
(C) IgE
(D) IgM
261. C1 component of classical complement pathway is made up of
(A) Complements 1q and 1r
(B) Complements 1q and 1s
(C) Complements 1r and 1s
(D) Complements 1q, 1r and 1s
262. The components of complement system are activated by
(A) Microsomal hydroxylation
(B) Phosphorylation
(C) Glycosylation
(D) Proteloysis
263. The component system forms a membrane attack complex made up of
(A) Complements 1q, 1r and 1s
(B) Complements 1, 2, 3 and 4
(C) Complements 5b, 6, 7 and 8
(D) Factors B and D
264. Factors B and D are required in
(A) The classical pathway of complement fixation
(B) The alternate complement pathway
(C) Both (A) and (B)
(D) None of these
265. The alternate complement pathway doesn’t involve
(A) Antigen-antibody complex
(B) Complement 3
(C) Factors B and D
(D) Membrane attack unit
266. Antibody diversity arises from
(A) Gene amplification
(B) Gene re-arrangement
(C) Alternative splicing
(D) All of these
267. A light chain gene is constructed from the following segments:
(A) Variable and constant segments
(B) Variable, joining and constant segments
(C) Variable, diversity and constant segments
(D) Variable, joining, diversity and constant segments
268. In metabolic point of view, amino acids are classified as
(A) Glycogenic
(B) Ketogenic
(C) Glycogenic or Ketogenic
(D) All of these
269. Diversity segments are present in
(A) Light chain genes
(B) Heavy chain genes
(C) Light and heavy chain genes
(D) None of these
270. Constant segments of heavy chains are of
(A) Five types
(B) Six types
(C) Seven types
(D) Eight types
271. Gamma heavy chains are of
(A) Two types
(B) Three types
(C) Four types
(D) Five types
272. Gamma heavy chains are present in
(A) IgA
(B) IgG
(C) IgM
(D) IgD
273. Heavy chains in IgD are of following type:
(A) Alpha
(B) Gamma
(C) Delta
(D) Epsilon
274. On exposure to any antigen, the first antibody to be formed is of the following class:
(A) IgA
(B) IgG
(C) IgM
(D) IgE
275. Constant segment genes of heavy chains are present in a cluster in which the first gene on side is (A) Alpha
(B) Gamma
(C) Delta
(D) None of these
276. Cell-mediated immunity is the function of
(A) B lymphocytes
(B) T lymphocytes
(C) Plasma cells
(D) Basophils
277. The most abundant T cells are
(A) Cytotoxic T cells
(B) Helper T cells
(C) Suppressor T cells
(D) Memory T cells
278. T cells can recognise
(A) Free antigens
(B) Antigens bound to cells
(C) Antigens bound to antibodies
(D) Antigens bound to MHC proteins
279. MHC proteins are unique to
(A) Each cell
(B) Each organ
(C) Each individual
(D) Each species
280. MHC class I proteins are present on the surface of
(A) B cells only
(B) T cells only
(C) Macrophages only
(D) All cells
281. MHC class I proteins, in conjunction with antigens are recognised by
(A) Cytotoxic T cells
(B) Helper T cells
(C) Suppressor T cells
(D) Memory T cells
(A) The classical pathway of complement fixation
(B) The alternate complement pathway
(C) Both (A) and (B)
(D) None of these
265. The alternate complement pathway doesn’t involve
(A) Antigen-antibody complex
(B) Complement 3
(C) Factors B and D
(D) Membrane attack unit
266. Antibody diversity arises from
(A) Gene amplification
(B) Gene re-arrangement
(C) Alternative splicing
(D) All of these
267. A light chain gene is constructed from the following segments:
(A) Variable and constant segments
(B) Variable, joining and constant segments
(C) Variable, diversity and constant segments
(D) Variable, joining, diversity and constant segments
268. In metabolic point of view, amino acids are classified as
(A) Glycogenic
(B) Ketogenic
(C) Glycogenic or Ketogenic
(D) All of these
269. Diversity segments are present in
(A) Light chain genes
(B) Heavy chain genes
(C) Light and heavy chain genes
(D) None of these
270. Constant segments of heavy chains are of
(A) Five types
(B) Six types
(C) Seven types
(D) Eight types
271. Gamma heavy chains are of
(A) Two types
(B) Three types
(C) Four types
(D) Five types
272. Gamma heavy chains are present in
(A) IgA
(B) IgG
(C) IgM
(D) IgD
273. Heavy chains in IgD are of following type:
(A) Alpha
(B) Gamma
(C) Delta
(D) Epsilon
274. On exposure to any antigen, the first antibody to be formed is of the following class:
(A) IgA
(B) IgG
(C) IgM
(D) IgE
275. Constant segment genes of heavy chains are present in a cluster in which the first gene on side is (A) Alpha
(B) Gamma
(C) Delta
(D) None of these
276. Cell-mediated immunity is the function of
(A) B lymphocytes
(B) T lymphocytes
(C) Plasma cells
(D) Basophils
277. The most abundant T cells are
(A) Cytotoxic T cells
(B) Helper T cells
(C) Suppressor T cells
(D) Memory T cells
278. T cells can recognise
(A) Free antigens
(B) Antigens bound to cells
(C) Antigens bound to antibodies
(D) Antigens bound to MHC proteins
279. MHC proteins are unique to
(A) Each cell
(B) Each organ
(C) Each individual
(D) Each species
280. MHC class I proteins are present on the surface of
(A) B cells only
(B) T cells only
(C) Macrophages only
(D) All cells
281. MHC class I proteins, in conjunction with antigens are recognised by
(A) Cytotoxic T cells
(B) Helper T cells
(C) Suppressor T cells
(D) Memory T cells
282. MHC class II proteins are present on the surface of
(A) All cells
(B) B lymphocytes only
(C) Macrophages only
(D) Macrophages and B lymphocytes
283. MHC Class II proteins, in conjunction with antigens, are recognised by
(A) Cytotoxic T cells
(B) Helper T cells
(C) Suppressor T cells
(D) Memory T cells
284. CD 8 is a transmembrane glycoprotein present in
(A) Cytotoxic T cells
(B) Helper T cells
(C) Suppressor T cells
(D) Memory T cells
285. CD 4 is a transmembrane glycoprotein present in
(A) Cytotoxic T cells
(B) Helper T cells
(C) Suppressor T cells
(D) Memory T cells
286. CD 3 complex and p 56lck proteins are present in
(A) Cytotoxic T cells
(B) Helper T cells
(C) Both (A) and (B)
(D) None of these
287. Cytotoxic T cells release
(A) Perforins
(B) Interleukins
(C) Colony stimulating factors
(D) Tumour necrosis factor
288. Helper T cells release
(A) Interleukins
(B) Colony stimulating factors
(C) Tumour necrosis factor
(D) All of these
289. MHC Class III proteins include
(A) Immunoglobulins
(B) Components of complement system
(C) T cells receptors
(D) CD4 and CD8 proteins
290. Human immunodeficiency virus destroys
(A) Cytotoxic T cells
(B) Helper T cells
(C) B cells
(D) Plasma cells
291. In allergic diseases, the concentration of the following is increased in plasma:
(A) IgA
(B) IgG
(C) IgD
(D) IgE
292. IgE has a tendency to attach to
(A) Basophils
(B) Mast cells
(C) Both (A) and (B)
(D) None of these
293. Reaginic antibody is
(A) IgA
(B) IgG
(C) IgD
(D) IgE
294. Active immunity can be produced by administration of
(A) Killed bacteria or viruses
(B) Live attenuated bacteria or viruses
(C) Toxoids
(D) All of these
295. Passive immunity can be produced by administration of
(A) Pure antigens
(B) Immunoglobulins
(C) Toxoids
(D) Killed bacteria or viruses
296. Helper T cells release all the following except
(A) Interleukins
(B) Colony stimulating factors
(C) Perforins
(D) Tumour necrosis factor
297. IgG cleaved by papain into
(A) Two light and two heavy chains
(B) Two Fab and one Fc fragments
(C) Two pairs of one light and one heavy chain each
(D) One Fab and two Fc fragments
298. Bence-Jones protein is
(A) An immunoglobulin
(B) A dimer of heavy chains
(C) A dimer of light chains
(D) A dimer of one heavy and one light chains
No comments