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Bio Chemistry MCQs


Bio Chemistry MCQs 









1. The functions of plasma albumin are

  • (A) Osmosis
  • (B) Transport
  • (C) Immunity
  • (D) both (A )and (B)


2. Amino acid with side chain containing basic groups is

  • (A) 2-Amino 5-guanidovaleric acid
  • (B) 2-Pyrrolidine carboxylic acid
  • (C) 2-Amino 3-mercaptopropanoic acid
  • (D) 2-Amino propanoic acid


3. An example of α-amino acid not present in proteins but essential in mammalian metabolism is

  • (A) 3-Amino 3-hydroxypropanoic acid
  • (B) 2-Amino 3-hydroxybutanoic acid
  • (C) 2-Amino 4-mercaptobutanoic acid
  • (D) 2-Amino 3-mercaptopropanoic acid


 4. An essential amino acid in man is

  • (A) Aspartate
  • (B) Tyrosine
  • (C) Methionine
  • (D) Serine


5. Non essential amino acids

  • (A) Are not components of tissue proteins
  • (B) May be synthesized in the body from essential amino acids
  • (C) Have no role in the metabolism
  • (D) May be synthesized in the body in diseased states


6. Which one of the following is semiessential amino acid for humans?

  • (A) Valine
  • (B) Arginine
  • (C) Lysine
  • (D) Tyrosine


7. An example of polar amino acid is

  •  (A) Alanine
  •  (B) Leucine
  •  (C) Arginine
  •  (D) Valine


8. The amino acid with a nonpolar side chain is

  • (A) Serine
  •  (B) Valine
  • (C) Asparagine
  •  (D) Threonine


9. A ketogenic amino acid is

  •  (A) Valine
  • (B) Cysteine
  •  (C) Leucine
  •  (D) Threonine


10. An amino acid that does not form an α- helix is

  • (A) Valine
  •  (B) Proline
  • (C) Tyrosine
  •  (D) Tryptophan


11. An amino acid not found in proteins is

  •  (A) β-Alanine
  •  (B) Proline
  •  (C) Lysine
  •  (D) Histidine


12. In mammalian tissues serine can be a biosynthetic precursor of

  • (A) Methionine
  • (B) Glycine
  • (C) Tryptophan
  • (D) Phenylalanine


13. A vasodilating compound is produced by the decarboxylation of the amino acid:

  • (A) Arginine
  • (B) Aspartic acid
  • (C) Glutamine
  • (D) Histidine


14. Biuret reaction is specific for

  • (A) –CONH-linkages
  • (B) –CSNH2 group
  • (C) –(NH)NH2 group
  • (D) All of these


 15. Sakaguchi’s reaction is specific for

  •  (A) Tyrosine
  •  (B) Proline
  • (C) Arginine
  • (D) Cysteine


16. Million-Nasse’s reaction is specific for the amino acid:

  • (A) Tryptophan
  • (B) Tyrosine
  • (C) Phenylalanine
  • (D) Arginine


17. Ninhydrin with evolution of CO2 forms a blue complex with

  • (A) Peptide bond
  • (B) α-Amino acids
  • (C) Serotonin
  • (D) Histamine


18. The most of the ultraviolet absorption of proteins above 240 nm is due to their content of

  •  (A) Tryptophan
  •  (B) Aspartate
  •  (C) Glutamate
  •  (D) Alanine


19. Which of the following is a dipeptide?

  • (A) Anserine
  •  (B) Glutathione
  •  (C) Glucagon
  •  (D) β -Lipoprotein


20. Which of the following is a tripeptide?

  •  (A) Anserine
  •  (B) Oxytocin
  •  (C) Glutathione
  • (D) Kallidin

21. A peptide which acts as potent smooth muscle hypotensive agent is

  •  (A) Glutathione
  •  (B) Bradykinin
  • (C) Tryocidine
  • (D) Gramicidin-s


22. A tripeptide functioning as an important reducing agent in the tissues is

  • (A) Bradykinin
  • (B) Kallidin
  • (C) Tyrocidin
  • (D) Glutathione


23. An example of metalloprotein is

  • (A) Casein
  • (B) Ceruloplasmin
  • (C) Gelatin
  • (D) Salmine


24. Carbonic anhydrase is an example of

  • (A) Lipoprotein
  • (B) Phosphoprotein
  • (C) Metalloprotein
  • (D) Chromoprotein


25. An example of chromoprotein is

  • (A) Hemoglobin
  • (B) Sturine
  • (C) Nuclein
  • (D) Gliadin


26. An example of scleroprotein is

  • (A) Zein
  • (B) Keratin
  • (C) Glutenin
  • (D) Ovoglobulin


27. Casein, the milk protein is

  • (A) Nucleoprotein
  • (B) Chromoprotein
  • (C) Phosphoprotein
  • (D) Glycoprotein


28. An example of phosphoprotein present in egg yolk is

  • (A) Ovoalbumin
  • (B) Ovoglobulin
  • (C) Ovovitellin
  • (D) Avidin


29. A simple protein found in the nucleoproteins of the sperm is

  • (A) Prolamine
  • (B) Protamine
  • (C) Glutelin
  • (D) Globulin


30. Histones are

  • (A) Identical to protamine
  • (B) Proteins rich in lysine and arginine
  • (C) Proteins with high molecular weight
  • (D) Insoluble in water and very dilute acids


31. The protein present in hair is

  • (A) Keratin
  • (B) Elastin
  • (C) Myosin
  • (D) Tropocollagen


32. The amino acid from which synthesis of the protein of hair keratin takes place is

  • (A) Alanine
  • (B) Methionine
  • (C) Proline
  • (D) Hydroxyproline


33. In one molecule of albumin the number of amino acids is

  • (A) 510
  • (B) 590
  • (C) 610
  • (D) 650


34. Plasma proteins which contain more than 4% hexosamine are

  • (A) Microglobulins
  • (B) Glycoproteins
  • (C) Mucoproteins
  • (D) Orosomucoids


35. After re leas ing O2 at the tissues, hemoglobin transports

  • (A) CO2 and protons to the lungs
  • (B) O2 to the lungs
  • (C) CO2 and protons to the tissue
  • (D) Nutrients


36. Ehlers-Danlos syndrome characterized by hypermobile joints and skin abnormalities is due to

  • (A) Abnormality in gene for procollagen
  • (B) Deficiency of lysyl oxidase
  • (C) Deficiency of prolyl hydroxylase
  • (D) Deficiency of lysyl hydroxylase


37. Proteins are soluble in

  • (A) Anhydrous acetone
  • (B) Aqueous alcohol
  • (C) Anhydrous alcohol
  • (D) Benzene


38. A cereal protein soluble in 70% alcohol but insoluble in water or salt solution is

  • (A) Glutelin
  • (B) Protamine
  • (C) Albumin
  • (D) Gliadin


39. Many globular proteins are stable in solution inspite they lack in

  • (A) Disulphide bonds
  • (B) Hydrogen bonds
  • (C) Salt bonds
  • (D) Non polar bonds


40. The hydrogen bonds between peptide linkages of a protein molecules are interfered by

  • (A) Guanidine
  • (B) Uric acid
  • (C) Oxalic acid
  • (D) Salicylic acid

41. Globular proteins have completely folded, coiled polypeptide chain and the axial ratio (ratio of length to breadth) is

  • (A) Less than 10 and generally not greater than 3–4
  • (B) Generally 10
  • (C) Greater than 10 and generally 20
  • (D) Greater than 10


42. Fibrous proteins have axial ratio

  • (A) Less than 10
  • (B) Less than 10 and generally not greater than 3–4
  • (C) Generally 10
  • (D) Greater than 10


43. Each turn of α-helix contains the amino acid residues (number):

  •  (A) 3.6
  • (B) 3.0
  • (C) 4.2
  • (D) 4.5


44. Distance traveled per turn of α−helix in nm is

  • (A) 0.53
  • (B) 0.54
  • (C) 0.44
  • (D) 0.48


45. Along the α-helix each amino acid residue advances in nm by

  • (A) 0.15
  • (B) 0.10
  • (C) 0.12
  • (D) 0.20


46. The number of helices present in a collagen molecule is

  • (A) 1
  • (B) 2
  • (C) 3
  • (D) 4


47. In proteins the α-helix and β-pleated sheet are examples of

  • (A) Primary structure
  • (B) Secondary structure
  • (C) Tertiary structure
  • (D) Quaternary structure


48. The a-helix of proteins is

  • (A) A pleated structure
  • (B) Made periodic by disulphide bridges
  • (C) A non-periodic structure
  • (D) Stabilised by hydrogen bonds between NH and CO groups of the main chain

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