BIO CHEMISTRY MCQs
BIO CHEMISTRY MCQs
1. Which of the following metabolite integrates glucose
and fatty acid metabolism?
(A) Acetyl CoA
(B) Pyruvate
(C) Citrate
(D) Lactate
2. Cerebrosides consist of mostly of this sugar:
(A) Glucose
(B) Fructose
(C) Galactose
(D) Arabinose
3. Glucose will be converted into fatty acids if the diet has excess of
(A) Carbohydrates
(B) Proteins
(C) Fat
(D) Vitamins
4. The purple ring of Molisch reaction is due to
(A) Furfural
(B) Furfural + α Napthol
(C) °C Napthol
(D) Furfurol + H2SO4 + α -Naphthol
5. One of the following enzymes does not change glycogen synthase a to b.
(A) Glycogen synthase kinases 3, 4, 5
(B) Ca2+ calmodulin phosphorylase kinase
(C) Ca2+ calmodulin dependent protein kinase
(D) Glycogen phosphorylase a
6. In EM pathway -2-phosphoglycerate is converted to
(A) Phospho enol pyruvate
(B) Enol pyruvate
(C) Di hydroxy acetone phosphate (DHAP)
(D) 1,3 bisphosphoglycerate
7. An aneplerotic reaction which sustains the availability of oxaloacetate is the carboxylation of (A) Glutamate
(B) Pyruvate
(C) Citrate
(D) Succinate
8. Specific test for ketohexoses:
(A) Seliwanoff’s test
(B) Osazone test
(C) Molisch test
(D) None of these
9. Two important byproducts of HMP shunt are
(A) NADH and pentose sugars
(B) NADPH and pentose sugars
(C) Pentose sugars and 4 membered sugars
(D) Pentose sugars and sedoheptulose
(A) Acetyl CoA
(B) Pyruvate
(C) Citrate
(D) Lactate
2. Cerebrosides consist of mostly of this sugar:
(A) Glucose
(B) Fructose
(C) Galactose
(D) Arabinose
3. Glucose will be converted into fatty acids if the diet has excess of
(A) Carbohydrates
(B) Proteins
(C) Fat
(D) Vitamins
4. The purple ring of Molisch reaction is due to
(A) Furfural
(B) Furfural + α Napthol
(C) °C Napthol
(D) Furfurol + H2SO4 + α -Naphthol
5. One of the following enzymes does not change glycogen synthase a to b.
(A) Glycogen synthase kinases 3, 4, 5
(B) Ca2+ calmodulin phosphorylase kinase
(C) Ca2+ calmodulin dependent protein kinase
(D) Glycogen phosphorylase a
6. In EM pathway -2-phosphoglycerate is converted to
(A) Phospho enol pyruvate
(B) Enol pyruvate
(C) Di hydroxy acetone phosphate (DHAP)
(D) 1,3 bisphosphoglycerate
7. An aneplerotic reaction which sustains the availability of oxaloacetate is the carboxylation of (A) Glutamate
(B) Pyruvate
(C) Citrate
(D) Succinate
8. Specific test for ketohexoses:
(A) Seliwanoff’s test
(B) Osazone test
(C) Molisch test
(D) None of these
9. Two important byproducts of HMP shunt are
(A) NADH and pentose sugars
(B) NADPH and pentose sugars
(C) Pentose sugars and 4 membered sugars
(D) Pentose sugars and sedoheptulose
10. Pyruvate dehydrogenase complex and α-ketoglutarate
dehydrogenase complex require the following for their oxidative
decarboxylation:
(A) COASH and Lipoic acid
(B) NAD+ and FAD
(C) COASH and TPP
(D) COASH, TPP,NAD+,FAD, Lipoate
11. The four membered aldose sugar phosphate formed in HMP shunt pathway is
(A) Xylulose P
(B) Erythrulose P
(C) Erythrose P
(D) Ribulose P
12. Cane sugar (Sucrose) injected into blood is
(A) changed to fructose
(B) changed to glucose
(C) undergoes no significant change
(D) changed to glucose and fructose
13. Pentose production is increased in
(A) HMP shunt
(B) Uromic acid pathway
(C) EM pathway
(D) TCA cycle
14. Conversion of Alanine to carbohydrate is termed:
(A) Glycogenesis
(B) Gluconeogenesis
(C) Glycogenolysis
(D) Photosynthesis
15. The following is an enzyme required for glycolysis:
(A) Pyruvate kinase
(B) Pyruvate carboxylase
(C) Glucose-6-phosphatase
(D) Glycerokinase
16. Our body can get pentoses from
(A) Glycolytic pathway
(B) Uromic acid pathway
(C) TCA cycle
(D) HMP shunt
(A) COASH and Lipoic acid
(B) NAD+ and FAD
(C) COASH and TPP
(D) COASH, TPP,NAD+,FAD, Lipoate
11. The four membered aldose sugar phosphate formed in HMP shunt pathway is
(A) Xylulose P
(B) Erythrulose P
(C) Erythrose P
(D) Ribulose P
12. Cane sugar (Sucrose) injected into blood is
(A) changed to fructose
(B) changed to glucose
(C) undergoes no significant change
(D) changed to glucose and fructose
13. Pentose production is increased in
(A) HMP shunt
(B) Uromic acid pathway
(C) EM pathway
(D) TCA cycle
14. Conversion of Alanine to carbohydrate is termed:
(A) Glycogenesis
(B) Gluconeogenesis
(C) Glycogenolysis
(D) Photosynthesis
15. The following is an enzyme required for glycolysis:
(A) Pyruvate kinase
(B) Pyruvate carboxylase
(C) Glucose-6-phosphatase
(D) Glycerokinase
16. Our body can get pentoses from
(A) Glycolytic pathway
(B) Uromic acid pathway
(C) TCA cycle
(D) HMP shunt
17. Conversion of glucose to glucose-6- phosphate in human
liver is by
(A) Hexokinase only
(B) Glucokinase only
(C) Hexokinase and glucokinase
(D) Glucose-6-phosphate dehydrogenase
18. The following is an enzyme required for glycolysis:
(A) Pyruvate kinase
(B) Pyruvate carboxylase
(C) Glucose-6-phosphatose
(D) Glycerokinase
19. The normal glucose tolerance curve reaches peak is
(A) 15 min
(B) 1 hr
(C) 2 hrs
(D) 2 ½ hrs
20. Oxidative decarboxylation of pyruvate requires
(A) NADP+
(B) Cytichromes
(C) pyridoxal phosphate
(D) COASH
21. Glucose tolerance is increased in
(A) Diabetes mellitus
(B) Adrenalectomy
(C) Acromegaly
(D) Thyrotoxicosis
22. Glucose tolerance is decreased in
(A) Diabetes mellitus
(B) Hypopituitarisme
(C) Addison’s disease
(D) Hypothyroidism
23. During glycolysis, Fructose 1, 6 diphosphate is decomposed by the enzyme:
(A) Enolase a
(B) Fructokinase
(C) Aldolase
(D) Diphosphofructophosphatose
24. The following enzyme is required for the hexose monophosphate shunt pathway:
(A) Glucose-6-phosphatase
(B) Phosphorylase
(C) Aldolase
(D) Glucose-6-phosphate dehydrogenase
(A) Hexokinase only
(B) Glucokinase only
(C) Hexokinase and glucokinase
(D) Glucose-6-phosphate dehydrogenase
18. The following is an enzyme required for glycolysis:
(A) Pyruvate kinase
(B) Pyruvate carboxylase
(C) Glucose-6-phosphatose
(D) Glycerokinase
19. The normal glucose tolerance curve reaches peak is
(A) 15 min
(B) 1 hr
(C) 2 hrs
(D) 2 ½ hrs
20. Oxidative decarboxylation of pyruvate requires
(A) NADP+
(B) Cytichromes
(C) pyridoxal phosphate
(D) COASH
21. Glucose tolerance is increased in
(A) Diabetes mellitus
(B) Adrenalectomy
(C) Acromegaly
(D) Thyrotoxicosis
22. Glucose tolerance is decreased in
(A) Diabetes mellitus
(B) Hypopituitarisme
(C) Addison’s disease
(D) Hypothyroidism
23. During glycolysis, Fructose 1, 6 diphosphate is decomposed by the enzyme:
(A) Enolase a
(B) Fructokinase
(C) Aldolase
(D) Diphosphofructophosphatose
24. The following enzyme is required for the hexose monophosphate shunt pathway:
(A) Glucose-6-phosphatase
(B) Phosphorylase
(C) Aldolase
(D) Glucose-6-phosphate dehydrogenase
25 Dehydrogenase enzymes of the hexose monophosphate shunt are
(A) NAD+ specific
(B) NADP+ specific
(C) FAD specific
(D) FMN specific
26. Under anaerobic conditions the glycolysis of one mole of glucose yields ______moles of ATP. (A) One
(B) Two
(C) Eight
(D) Thirty
27. Glycogen is converted to glucose-1- phosphate by
(A) UDPG transferase
(B) Branching enzyme
(C) Phosphorylase
(D) Phosphatase
28. Which of the following is not an enzyme involved in glycolysis?
(A) Euolase
(B) Aldolose
(C) Hexokinase
(D) Glucose oxidase
29. Tricarboxylic acid cycle to be continuous requires the regeneration of
(A) Pyruvic acid
(B) oxaloacetic acid
(C) α-oxoglutaric acid
(D) Malic acid
30. Dehydrogenation of succinic acid to fumaric acid requires the following hydrogen carrier:
(A) NAD+
(B) NADP+
(C) flavoprotein
(D) Glutathione
31. The tissues with the highest total glycogen content are
(A) Muscle and kidneys
(B) Kidneys and liver
(C) Liver and muscle
(D) Brain and Liver
32. Rothera test is not given by
(A) β-hydroxy butyrate
(B) bile salts
(C) Glucose
(D) None of these
33. Gluconeogenesis is increased in the following condition:
(A) Diabetes insipidus
(B) Diabetes Mellitus
(C) Hypothyroidism
(D) Liver diseases
34. The oxidation of lactic acid to pyruvic acid requires the following vitamin derivative as the hydrogen carrier.
(A) Lithium pyrophosphate
(B) Coenyzme A
(C) NAD+
(D) FMN
35. Physiological glycosuria is met with in
(A) Renal glycosuria
(B) Alimentary glycosuria
(C) Diabetes Mellitus
(D) Alloxan diabetes
36. Two examples of substrate level phosphorylation in EM pathway of glucose metabolism are in the reactions of
(A) 1,3 bisphosphoglycerate and phosphoenol pyruvate
(B) Glucose-6 phosphate and Fructo-6-phosphate
(C) 3 phosphoglyceraldehyde and phosphoenolpyruvate
(D) 1,3 diphosphoglycerate and 2-phosphoglycerate
37. The number of molecules of ATP produced by the total oxidation of acetyl CoA in TCA cycle is (A) 6
(B) 8
(C) 10
(D) 12
38. Substrate level phosphorylation in TCA cycle is in step:
(A) Isocitrate dehydrogenase
(B) Malate dehydrogenase
(C) Aconitase
(D) Succinate thiokinase
39. Fatty acids cannot be converted into carbohydrates in the body as the following reaction is not possible.
(A) Conversion of glucose-6-phosphate into glucose
(B) Fructose 1,6-bisphosphate to fructose-6- phosphate
(C) Transformation of acetyl CoA to pyruvate
(D) Formation of acetyl CoA from fatty acids
40. Tissues form lactic acid from glucose. This phenomenon
is termed as
(A) Aerobic glycolysis
(B) Oxidation
(C) Oxidative phosphorylation
(D) Anaerobic glycolysis
41. One molecule of glucose gives ______ molecules of CO2 in EM-TCA cycle.
(A) 6
(B) 3
(C) 1
(D) 2
42. One molecule of glucose gives ______ molecules of CO2 in one round of HMP shunt.
(A) 6
(B) 1
(C) 2
(D) 3
(A) Aerobic glycolysis
(B) Oxidation
(C) Oxidative phosphorylation
(D) Anaerobic glycolysis
41. One molecule of glucose gives ______ molecules of CO2 in EM-TCA cycle.
(A) 6
(B) 3
(C) 1
(D) 2
42. One molecule of glucose gives ______ molecules of CO2 in one round of HMP shunt.
(A) 6
(B) 1
(C) 2
(D) 3
43. The 4 rate limiting enzymes of gluconeogenesis are
(A) Glucokinase, Pyruvate carboxylae phosphoenol pyruvate carboxykinase and glucose-6-phosphatase
(B) Pyruvate carboxylase, phosphoenol pyruvate carboxykinase, fructose1,6 diphosphatase and glucose-6-phosphatase
(C) Pyruvate kinase, pyruvate carboxylase, phosphoenol pyruvate carboxykinase and glucose-6-phosphatase
(D) Phospho fructokinase, pyruvate carboxylase, phosphoenol pyruvate carboxykinase and fructose 1, 6 diphosphatase
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