BIO CHEMISTRY MCQs (PART 3) by General knowledge Solutions
BIO CHEMISTRY MCQs (PART 3) by General knowledge Solutions
1. In the type II (a) hyper lipoproteinemia there is
increase in
2. Normal fat content of liver is about _______ gms %.
3. Obesity is accumulation of _______ in the body.
4. The first lipoprotein to be secreted by the liver is
5. This lipoprotein removes cholesterol from the body
Correct Answer: A
6. When the stired triacylglycerol is lipolysed in the adipose tissue blood levels of _____ increased.
Correct Answer: C
7. All long chain fatty acids with even number of carbon atoms are oxidized to a pool of _________ by β-oxidation.
Correct Answer:B
8. The level of free fatty acids in plasma is increased by
Correct Answer:A
9. Cholesterol is excreted as such into ________.
- (A) Chylomicron bond
- (B) β
- (C) Pre beta
- (D) α
2. Normal fat content of liver is about _______ gms %.
- (A) 5
- (B) 8
- (C) 10
- (D) 15
3. Obesity is accumulation of _______ in the body.
- (A) Water
- (B) NaCl
- (C) Fat
- (D) Proteins
4. The first lipoprotein to be secreted by the liver is
- (A) VLDL
- (B) nascent VLDL
- (C) LDL
- (D) IDL
5. This lipoprotein removes cholesterol from the body
- (A) HDL
- (B) VLDL
- (C) IDL
- (D) Chylomicrons
Correct Answer: A
6. When the stired triacylglycerol is lipolysed in the adipose tissue blood levels of _____ increased.
- (A) FFA only
- (B) Glycerol only
- (C) Free fatty acids (FFA) and Glycerol
- (D) Triacyl glycero
Correct Answer: C
7. All long chain fatty acids with even number of carbon atoms are oxidized to a pool of _________ by β-oxidation.
- (A) CO2
- (B) Propionic acid
- (C) Acetic acid
- (D) Acetyl CoA
Correct Answer:B
8. The level of free fatty acids in plasma is increased by
- (A) Insulin
- (B) Caffeine
- (C) Glucose
- (D) Niacin
Correct Answer:A
9. Cholesterol is excreted as such into ________.
- (A) Urine
- (B) Faeces
- (C) Bile
- (D) Tears
Correct Answer:C
10. LCAT is
- (A) Lactose choline alamine transferse
- (B) Lecithin cholesterol acyl transferase
- (C) Lecithin carnitine acyl transferase
- (D) Lanoleate carbamoyl acyl transferase
Correct Answer:B
11. Cholesterol molecule has _______ carbon atoms.
- (A) 27
- (B) 21
- (C) 15
- (D) 12
Correct Answer:A
12. A hydrocarbon formed in cholesterol synthesis is
- (A) Mevalonate
- (B) HMG CoA
- (C) Squalene
- (D) Zymosterol
Correct Answer:C
13. While citrate is converted to isocitrate in the mitochondria, it is converted to _______ in the cytosol.
- (A) Acetyl CoA + oxaloacetate
- (B) Acetyl CoA + malonyl CoA
- (C) Acetyl CoA + Pyruvate
- (D) Acetyl CoA + acetoacetyl CoA
Correct Answer:D
14. Avidin is antigonistic to
- (A) Niacin
- (B) PABA
- (C) Biotin
- (D) Pantothenic acid
Correct Answer:B
15. CTP is required for the synthesis of
- (A) Fatty acids
- (B) Proteins
- (C) Phospholipids
- (D) Cholesterol
Correct Answer:C
16. Lysolecithin is formed from lecithin by the action of
- (A) Phospholipase A1
- (B) Phospholipase A2
- (C) Phospholipase C
- (D) Phospholipase D
Correct Answer:B
17. Fatty acids can not be converted into carbohydrates in the body, as the following reaction is not possible:
- (A) Conversion of glucose-6-phosphate into glucose
- (B) Fructose 1, 6 diphosphate to fructose-6- phosphate
- (C) Transformation of acetyl CoA to pyruvate
- (D) Formation of acetyl CoA from fatty acids
Correct Answer:A
18. Cholesterol circulates in blood stream chiefly as
- (A) Free cholesterol
- (B) Ester cholesterol
- (C) Low density lipoproteins
- (D) Low density lipoproteins and high density lipoproteins
Correct Answer:C
19. What is the sub cellular site for the β- oxidation of fatty acids?
- (A) Nucleus
- (B) Mitochondria
- (C) Lysosome
- (D) Cytosol
Correct Answer:A
20. A diet containing this fat is helpful in lowering the blood cholesterol level.
- (A) Unsaturated
- (B) Saturated
- (C) Vitamin enriched
- (D) Refined
Correct Answer:C
21. Phospholipase A2 is an enzyme which removes a fatty acid residue from lecithin to form
- (A) Lecithin fragments
- (B) Phosphotidic acid
- (C) Glyceryl phosphate
- (D) Lysolecithin
Correct Answer:C
22. Pancreatic lipose is an enzyme which hydrolyzes facts. It acts as a/an
- (A) peptidase
- (B) hydrolase
- (C) carbohydrates
- (D) dehydrogenase
Correct Answer:B
23. This interferes with cholesterol absorption
- (A) Lipoprotein lipase
- (B) Creatinase
- (C) 7-dehydrocholesterol
- (D) β-sitosterol
Correct Answer:C
24. The carbon chain of fatty acids is shortened by 2 carbon atoms at a time. This involves successive reactions catalysed by 4-enzymes. These act the following order:
- (A) Acetyl CoA dehydrogenase, β-OH acyl CoA dehydrogenase, enoyl hydrase, thiolose
- (B) Acyl CoA dehydrogenase, thiolase, enoyl hydrase, β-OH acyl CoA dehydrogenase
- (C) Acyl CoA dehydrogenase, thiolose, enoyl hydrase, β-OH acyl CoA dehydrogenase
- (D) Enoyl hydrase, β-OH acyl CoA dehydrogenase, acyl CoA dehydrogenase, thiolose,
Correct Answer:D
25. Acyl carrier protein is involved in the synthesis of
- (A) protein
- (B) glycogen
- (C) fatty acid outside the mitochondria
- (D) fatty acid in the mitochondria
Correct Answer:B
26. 1 molecule of palmitic acid on total oxidation to CO2 will yield molecules of ATP (as high energy bonds):
- (A) 129
- (B) 154
- (C) 83
- (D) 25
Correct Answer: A
27. HMG CoA is formed in the metabolism of
- (A) Cholesterol, ketones and leucine
- (B) Cholesterol, fatty acid and Leucine
- (C) Lysine, Lecuine and Isoleucine
- (D) Ketones, Leucine and Lysine
Correct Answer:D
28. NADPH is produced when this enzyme acts
- (A) Pyruvate dehydrogenase
- (B) Malic enzyme
- (C) Succinate dehydrogenase
- (D) Malate dehydrogenase
Correct Answer:B
29. As a result of each oxidation a long chain fatty acid is cleaved to give
- (A) An acid with 3-carbon less and propionyl CoA
- (B) An acid with 2-carbon less and acetyl CoA
- (C) An acid with 2-carbon less and acetyl CoA
- (D) An acid with 4-carbon and butyryl CoA
Correct Answer:B
30. Liposomes are
- (A) Lipid bilayered
- (B) Water in the middle
- (C) Carriers of drugs
- (D) All of these
Correct Answer:D
31. Long chain fatty acyl CoA esters are transported across the mitochondrial membrane by
- (A) cAMP
- (B) Prostaglandin
- (C) Carnitine
- (D) Choline
Correct Answer:C
32. The acetyl CoA formed on β-oxidation of all long chain fatty acids is metabolized under normal circumstances to
- (A) CO2 and water
- (B) Cholesterol
- (C) Fatty acids
- (D) Ketone bodies
Correct Answer:A
33. Very low density lipoproteins are relatively rich in
- (A) Cholesterol
- (B) Triacyl glycerol
- (C) Free fatty acids
- (D) Phospholipids
Correct Answer: B
34. Neutral fat is stored in
- (A) Liver
- (B) Pancreas
- (C) Adipose tissue
- (D) Brain
Correct Answer:G
35. A pathway that requires NADPH as a cofactor is
- (A) Fatty acid oxidation
- (B) Extra mitochondrial denovo fatty acid synthesis
- (C) Ketone bodies formation
- (D) Glycogenesis
Correct Answer:B
36. The ‘Committed step’ in the biosynthesis of cholesterol from acetyl CoA is
- (A) Formation of acetoacetyl CoA from acetyl CoA
- (B) Formation of mevalonate from HMG CoA
- (C) Formation of HMG CoA from acetyl CoA and acetoacetyl CoA
- (D) Formation of squalene by squalene synthetase
Correct Answer:B
38. In β-Oxidation of fatty acids, which of the following are utilized as coenzymes?
- (A) NAD+ and NADP+
- (B) FADH2 and NADH + H+
- (C) FAD and FMN
- (D) FAD and NAD+
Correct Answer: D
39. The most important source of reducing equivalents for FA synthesis on the liver is
- (A) Glycolysis
- (B) HMP-Shunt
- (C) TCA cycle
- (D) Uronic acid pathway
Correct Answer:B
40. All of the following tissue are capable of using ketone bodies except
- (A) Brain
- (B) Renal cortex
- (C) R.B.C.
- (D) Cardiac muscle
Correct Answer:C
41. The major source of cholesterol in arterial smooth muscle cells is from
- (A) IDL
- (B) LDL
- (C) HDL
- (D) Chylomicrons
Correct Answer:B
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